Evidence map›Paper›PMID 32808881›Full record

Trial reportTrends in hearing

Cochlear Implantation in Cases of Asymmetric Hearing Loss: Subjective Benefit, Word Recognition, and Spatial Hearing.

Margaret T Dillon, Emily Buss, Meredith A Rooth, English R King, Sarah A McCarthy, Andrea L Bucker, Ellen J Deres, Margaret E Richter, Nicholas J Thompson, Michael W Canfarotta and 3 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. A Prospective Multicenter Post-Market Study Evaluating the Safety and Effectiveness of Cochlear Implantation in Adults With Single-Sided Deafness.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026
    Article
  2. Article
  3. Improvements in Perceived Abilities and Speech Recognition in Quiet and Noise for Older Adults With Single-sided Deafness or Asymmetric Hearing Loss: A Multi-center Investigation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026
    Article
  4. Article
  5. Evaluation of medium-term cochlear implant use in patients with asymmetric hearing loss.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Margaret T DillonDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.ORCID 0000-0003-4344-283X
Emily BussDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
Meredith A RoothDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
English R KingDepartment of Audiology, UNC Health Care, Chapel Hill, North Carolina, United States.
Sarah A McCarthyDepartment of Audiology, UNC Health Care, Chapel Hill, North Carolina, United States.
Andrea L BuckerDepartment of Audiology, UNC Health Care, Chapel Hill, North Carolina, United States.
Ellen J DeresDepartment of Audiology, UNC Health Care, Chapel Hill, North Carolina, United States.
Margaret E RichterDivision of Speech & Hearing Sciences, Department of Allied Health, University of North Carolina at Chapel Hill.
Nicholas J ThompsonDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
Michael W CanfarottaDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
Brendan P O'ConnellDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
Harold C PillsburyDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
Kevin D BrownDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill.
University of North Carolina at Chapel Hill · USUniversity of North Carolina Health Care · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
NCATS NIH HHS UL1 TR002489
6 · The paper itself

Abstract

A prospective clinical trial evaluated the effectiveness of cochlear implantation in adults with asymmetric hearing loss (AHL). Twenty subjects with mild-to-moderate hearing loss in the better ear and moderate-to-profound hearing loss in the poorer ear underwent cochlear implantation of the poorer hearing ear. Subjects were evaluated preoperatively and at 1, 3, 6, 9, and 12 months post-activation. Preoperative performance was evaluated unaided, with traditional hearing aids (HAs) or with a bone-conduction HA. Post-activation performance was evaluated with the cochlear implant (CI) alone or in combination with a contralateral HA (bimodal). Test measures included subjective benefit, word recognition, and spatial hearing (i.e., localization and masked sentence recognition). Significant subjective benefit was reported as early as the 1-month interval, indicating better performance with the CI compared with the preferred preoperative condition. Aided word recognition with the CI alone was significantly improved at the 1-month interval compared with preoperative performance with an HA and continued to improve through the 12-month interval. Subjects demonstrated early, significant improvements in the bimodal condition on the spatial hearing tasks compared with baseline preoperative performance tested unaided. The magnitude of the benefit was reduced for subjects with AHL when compared with published data on CI users with normal hearing in the contralateral ear; this finding may reflect significant differences in age at implantation and hearing sensitivity across cohorts.

Indexed as

Cochlear ImplantationCochlear ImplantsHearing AidsHearing LossSound LocalizationSpeech PerceptionAdultHumansProspective StudiesTreatment Outcomebimodalbinaural hearingcochlear implantsingle-sided deafnessspatial release from maskingunilateral hearing loss

Identifiers

PMID32808881
PMCPMC7586262
OpenAlexW3077933764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.