ReviewSLAS technology2020
The Virological, Immunological, and Imaging Approaches for COVID-19 Diagnosis and Research.
Review in SLAS technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Recent Advancements in Metal-Organic Framework-Based Microfluidic Chips for Biomedical Applications.Micromachines · 2025Review
- Novel metal-organic framework biosensing platform for detection of COVID-19 RNA.Scientific reports · 2024Article
- A multi-organ map of the human immune system across age, sex and ethnicity.bioRxiv : the preprint server for biology · 2024Article
- Multiplex Detection of RNA Viruses Based on Ligation Reaction and Universal PCR Amplification.Current microbiology · 2024Article
- COVID-19: detection methods in post-mortem samples.Pathologica · 2023Review
- Review
- Comparison of the SARS-CoV-2 BD Veritor Nasal Antigen Test with Nasopharyngeal Reverse Transcription-PCR in Symptomatic Patients.Microbiology spectrum · 2022Article
- Microfluidic Point-of-Care (POC) Devices in Early Diagnosis: A Review of Opportunities and Challenges.Sensors (Basel, Switzerland) · 2022Review
- COVID-19 Diagnostics: A Panoramic View on Its Present Scenario, Challenges and Solutions.Proceedings of the National Academy of Sciences, India. Section B · 2022Review
- Navigating the cellular landscape in tissue: Recent advances in defining the pathogenesis of human disease.Computational and structural biotechnology journal · 2022Review
- Performance of the T-SPOTInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Article
- FDG PET/CT imaging features and clinical utility in COVID-19.Clinical imaging · 2021Article
- A Review on the Development of Gold and Silver Nanoparticles-Based Biosensor as a Detection Strategy of Emerging and Pathogenic RNA Virus.Sensors (Basel, Switzerland) · 2021Review
- Urgent care center wait times increase for COVID-19 results in August 2020, with rapid testing availability limited.BMC health services research · 2021Article
- Acupuncture for COVID-19 patient after ventilator weaning: A protocol for systematic review and meta-analysis.Medicine · 2020Article
- Advances in Technology to Address COVID-19.SLAS technology · 2020Article
- Prolonged viral shedding and antibody persistence in patients with COVID-19.Microbes and infectionArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2019, a novel coronavirus (SARS-CoV-2) was found to cause a highly contagious disease characterized by pneumonia. The disease (COVID-19) quickly spread around the globe, escalating to a global pandemic. In this review, we discuss the virological, immunological, and imaging approaches harnessed for COVID-19 diagnosis and research. COVID-19 shares many clinical characteristics with other respiratory illnesses.Accurate and early detection of the infection is pivotal to controlling the outbreak, as this enables case identification, isolation, and contact tracing. We summarize the available literature on current laboratory and point-of-care diagnostics, highlight their strengths and limitations, and describe the emerging diagnostic approaches on the horizon.We also discuss the various research techniques that are being used to evaluate host immunity in laboratory-confirmed patients. Additionally, pathological imaging of tissue samples from affected patients has a critical role in guiding investigations on this disease. Conventional techniques, such as immunohistochemistry and immunofluorescence, have been frequently used to characterize the immune microenvironment in COVID-19. We also outline the emerging imaging techniques, such as the RNAscope, which might also aid in our understanding of the significance of COVID-19-specific biomarkers, such as the angiotensin-converting enzyme 2 (ACE2) cellular receptor.Overall, great progress has been made in COVID-19 research in a short period. Extensive, global collation of our current knowledge of SARS-CoV-2 will provide insights into novel treatment modalities, such as monoclonal antibodies, and support the development of a SARS-CoV-2 vaccine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.