ReviewChemistry, an Asian journal2020
Metal Nanoparticles-Enhanced Biosensors: Synthesis, Design and Applications in Fluorescence Enhancement and Surface-enhanced Raman Scattering.
Review in Chemistry, an Asian journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Advances in Cervical Cancer Diagnostics Based on Immunosensors: Innovative Approaches and Tumor Biomarkers.Current topics in medicinal chemistry · 2026Review
- Fluorescent silver hydrosol for the dual fluorometric sensing of gallic acid and CdRSC advances · 2025Article
- Ultra-Sensitive Detection of Bacterial Spores via SERS.ACS sensors · 2025Article
- High-sensitivity qPCR detection method based on silver flower-like LSPR-active material.Scientific reports · 2025Article
- Sensitive and Cost-Effective Tools in the Detection of Ovarian Cancer Biomarkers.Analytical science advances · 2024Article
- Blue light emitting graphene quantum dots/ Rhodamine B doped gold nanostars for ratiometric detection of methotrexate.Heliyon · 2024Article
- Multiscale modeling of surface enhanced fluorescence.Nanoscale advances · 2024Article
- A perspective on computer vision in biosensing.Biomicrofluidics · 2024Article
- Detection of pioglitazone based on dual-emission ratiometric fluorescence probe consisting of ZIF8 and to L-ASC-AuNP/DA nanoparticles.Mikrochimica acta · 2023Article
- Review
- Recent Developments on the Catalytic and Biosensing Applications of Porous Nanomaterials.Nanomaterials (Basel, Switzerland) · 2023Review
- Synthesis and Integration of Hybrid Metal Nanoparticles Covered with a Molecularly Imprinted Polymer Nanolayer by Photopolymerization.Sensors (Basel, Switzerland) · 2023Article
- Review
- Optical Processes behind Plasmonic Applications.Nanomaterials (Basel, Switzerland) · 2023Review
- Refractive Index Dependence of Fluorescence Enhancement in a Nanostructured Plasmonic Grating.Materials (Basel, Switzerland) · 2023Article
- Nanotechnology-Assisted Biosensors for the Detection of Viral Nucleic Acids: An Overview.Biosensors · 2023Review
- A Review on Gold Nanotriangles: Synthesis, Self-Assembly and Their Applications.Molecules (Basel, Switzerland) · 2022Review
- Plasmonic Modes and Fluorescence Enhancement Coupling Mechanism: A Case with a Nanostructured Grating.Nanomaterials (Basel, Switzerland) · 2022Article
- Plasmon-Enhanced Ultraviolet Luminescence in Colloid Solutions and Nanostructures Based on Aluminum and ZnO Nanoparticles.Nanomaterials (Basel, Switzerland) · 2022Article
- Selenium-based nanomaterials for biosensing applications.Materials advances · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metal nanoparticles (NP) that exhibit localized surface plasmon resonance play an important role in metal-enhanced fluorescence (MEF) and surface-enhanced Raman scattering (SERS). Among the optical biosensors, MEF and SERS stand out to be the most sensitive techniques to detect a wide range of analytes from ions, biomolecules to macromolecules and microorganisms. Particularly, anisotropic metal NPs with strongly enhanced electric field at their sharp corners/edges under a wide range of excitation wavelengths are highly suitable for developing the ultrasensitive plasmon-enhanced biosensors. In this review, we first highlight the reliable methods for the synthesis of anisotropic gold NPs and silver NPs in high yield, as well as their alloys and composites with good control of size and shape. It is followed by the discussion of different sensing mechanisms and recent advances in the MEF and SERS biosensor designs. This includes the review of surface functionalization, bioconjugation and (directed/self) assembly methods as well as the selection/screening of specific biorecognition elements such as aptamers or antibodies for the highly selective bio-detection. The right combinations of metal nanoparticles, biorecognition element and assay design will lead to the successful development of MEF and SERS biosensors targeting different analytes both in-vitro and in-vivo. Finally, the prospects and challenges of metal-enhanced biosensors for future nanomedicine in achieving ultrasensitive and fast medical diagnostics, high-throughput drug discovery as well as effective and reliable theranostic treatment are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.