Evidence map›Paper›PMID 32808295›Full record

ArticleClinical cardiology2020

Comparative effects of intensive ganglionated plexus ablation in treating paroxysmal atrial fibrillation and vasovagal syncope.

Xingfu Huang, Yanjia Chen, Yuli Huang, Hongxin Zhao, Liwei He, Zhenni Tan, Dingli Xu, Jian Peng

Open access · goldAbstract readComparative Study
In one paragraph

Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Fluoroscopy-free cardioneuroablation for functional bradycardia: a single-center experience.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Observational
  6. The Efficacy of Cardioneuroablation versus Midodrine in Patients with Vasovagal Syncope: Design and Rationale for the CAMPAIGN Trial.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Cardioneuroablation: the known and the unknown.Frontiers in cardiovascular medicine · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xingfu HuangDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-6823-4602
Yanjia ChenDepartment of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuli HuangDepartment of Cardiology, The First People's Hospital of Shunde, Foshan, China.
Hongxin ZhaoShanghai Synyi Medical Technology Co., Ltd, Shanghai, China.ORCID https://orcid.org/0000-0001-7906-2797
Liwei HeDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-5217-4190
Zhenni TanDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Dingli XuDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jian PengDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Nanfang Hospital · CNShanghai Senyi Medical Technology (China) · CNThe First People's Hospital of Shunde · CN

Funding

Natural Science Foundation of Guangdong Province 2018A030313637
6 · The paper itself

Abstract

backgroundGanglionated plexus (GP) ablation is used to treat atrial fibrillation (AF) and vasovagal syncope (VVS). However, the comparative effects of GP ablation in treating paroxysmal atrial fibrillation (PAF) and VVS have not been well studied.

objectiveThe purpose of this study was to investigate the effects of intensive GP ablation on PAF and VVS.

methodsPAF and VVS patients were enrolled in this study. Pulmonary vein isolation (PVI) was performed in the PAF group, and additional ablation was performed at GP sites. Anatomic ablation of left atrial GPs was performed in the VVS group. The primary endpoint was freedom from AF or other sustained atrial tachycardia and syncope recurrence.

resultsA total of 195 patients were enrolled: 146 patients with PAF, including eight patients with combined VVS (PAF group), and 49 patients with VVS (VVS group). Vasovagal response (VR) was achieved in 78 (53.4%) patients in the PAF group and 48 patients (98.0%) in the VVS group (P < .05). During the 17.8 ± 10.5 (range, 3-42) month follow-up, 126 (86.3%) patients were free of AF in the PAF group, and 45 (91.8%) patients in the VVS group had no syncope recurrence and significantly improved symptoms.

conclusionsAnatomically guided intensive GP ablation showed efficient clinical outcomes for both groups of patients. Compared with PAF patients, VVS patients had more VR during ablation in the left atrium. Furthermore, VR during ablation indicated a better prognosis in PAF patients.

Indexed as

AdultAtrial FibrillationCatheter AblationFemaleFollow-Up StudiesHeart Conduction SystemHumansMaleMiddle AgedProspective StudiesPulmonary VeinsRecurrenceSyncope, VasovagalTachycardia, ParoxysmalTreatment Outcomeatrial fibrillationcatheter ablationganglionated plexuspulmonary vein isolationvasovagal responsevasovagal syncope

Identifiers

PMID32808295
PMCPMC7661657
OpenAlexW3078621947

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.