Evidence map›Paper›PMID 32808267›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Corneal Repair Models in Mice: Epithelial/Mechanical Versus Stromal/Chemical Injuries.

Peipei Pan, Matilda F Chan

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Foxp3Experimental eye research · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Peipei PanDepartment of Ophthalmology, School of Medicine, University of California, San Francisco, CA, USA.
Matilda F ChanDepartment of Ophthalmology, School of Medicine, University of California, San Francisco, CA, USA. matilda.chan@ucsf.edu.
University of California, San Francisco · US

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAKKARAJU, APARNA · 1985 to 2024
$16.8M
Regulation of Corneal Repair by MetalloproteinasesR01EY022739 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, MATILDA F · 2013 to 2017
$2.0M
NEI NIH HHS P30 EY002162NEI NIH HHS R01 EY022739
6 · The paper itself

Abstract

The tissue response to injury is a complex process. The cornea is an excellent model for studying wound repair processes because of its simple anatomy, easy accessibility, and normal avascular state. Here, we describe two corneal repair models in mice: an epithelial/mechanical injury model and a stromal/chemical injury model. The two models induce different repair responses, and consequently enable the study of independent repair processes. Here, we describe how these two wound models may be used to study basic cellular and molecular mechanisms of corneal repair.

Indexed as

Wound HealingAnimalsCell- and Tissue-Based TherapyCorneaCorneal InjuriesEpithelium, CornealHumansMiceMice, Inbred C57BLCCL2/CCR2ChemokineCorneal injuryFibrosisInflammationMacrophageMMPNeovascularizationNeutrophil

Identifiers

PMID32808267
PMCPMC10448794
OpenAlexW3059022844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.