SynthesisEuropean geriatric medicine2020
Association between frailty and chronic pain among older adults: a systematic review and meta-analysis.
Synthesis in European geriatric medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07287501 (Efficacy of Pain Science Education Combined With Exercise in Older Adults With Chronic Pain), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Pain Science Education Combined With Exercise in Older Adults With Chronic Pain
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- The prevalence of oral frailty among older adults: a systematic review and meta‑analysis.European geriatric medicine · 2024Pooled it
- Chondromalacia patella increases the risk of herpes zoster: a population-based study.BMC musculoskeletal disorders · 2022Trial
- Impact of Pain Neuroscience Education Program in Community Physiotherapy Context on Pain Perception and Psychosocial Variables Associated with It in Elderly Persons: A Ranzomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Longitudinal associations of chronic pain and sleep quality with frailty progression in community-dwelling older adults.Aging clinical and experimental research · 2026Article
- Efficacy of Pain Neuroscience Education Combined with Exercise in Older Adults with Chronic Pain: Study Protocol for a Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Pain and frailty progression in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort study.The lancet. Healthy longevity · 2026Article
- The Hereditary Angioedema Frailty and Inflammation Score (HAE-FIS): A Preliminary Study on the Inter-Attack Chronic Burden.Journal of clinical medicine · 2026Article
- Construction and validation of oral frailty risk assessment model in elderly hospitalized patients.BMC oral health · 2026Article
- Association between chronic pain and frailty among Chinese adults aged ≥ 60 years: a cross-sectional study.Internal and emergency medicine · 2026Article
- Performance-Based and Self-Reported Frailty in Older Adults with or Without Fibromyalgia.European journal of investigation in health, psychology and education · 2026Article
- Association between frailty status and pain, balance, and quality of life in patients with lumbar spinal stenosis.Turkish journal of medical sciences · 2026Article
- Pain characteristics and incident frailty in community-dwelling older adults: dose-response relationships and sex differences in a longitudinal study on aging in Taiwan.Frontiers in public health · 2026Article
- From age to frailty: redefining chronic pain characterization.Aging clinical and experimental research · 2025Article
- Frailty-Informed Pain Management: A Clinical Imperative Beyond Chronological Age.Drugs & aging · 2025Article
- Association between chronic pain severity, falls, frailty and perceived health in older adults at risk of falls.European journal of medical research · 2025Article
- Association between pain expansion, physical activity, strength, motor problems and frailty risk in middle-aged and older European people: A cross-sectional study.Aging clinical and experimental research · 2025Article
- A Bayesian Structural Equation Model to Predict Quality of Life in European Older Adults.European journal of investigation in health, psychology and education · 2025Article
- Association between frailty and postherpetic neuralgia in the older adult with herpes zoster.Frontiers in public health · 2025Article
- The Interaction Among Depressive Symptoms, Pain, and Frailty in Middle-Aged and Older Adults: A Longitudinal Cross-Lagged Panel Analysis.Depression and anxiety · 2025Article
- Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study.Nature and science of sleep · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeFrailty and chronic pain are prevalent among older adults. However, no study has systematically reviewed the association between frailty and chronic pain in older adults. Therefore, we aimed to estimate the prevalence of frailty and prefrailty among older adults with chronic pain and review the longitudinal association between frailty status and chronic pain.
methodsEmbase, Medline, Pubmed, and Cochrane library were searched from inception to March 2020. The methodological quality of the studies was assessed using the Newcastle Ottawa Scale. Random effect models and Mantel-Haenszel weighting were adopted to synthesize the estimates.
resultsAmong the initial 846 articles retrieved, 24 were included in the review (12 cross-sectional, and 12 longitudinal). The pooled prevalence in persons with chronic pain was 18% (95% CI 14-23%; I
conclusionFrailty and prefrailty are common in persons with chronic pain. Chronic pain among non-frail older persons significantly predicts the incidence of frailty after an average follow-up of 5.8 years. Future studies should explore the efficacy of different pain management strategies in reducing physical frailty and clarify the association of other types of frailty (cognitive, social and psychological) with chronic pain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.