ArticleProbiotics and antimicrobial proteins2021
Characterization of Riboflavin-Producing Strains of Lactobacillus plantarum as Potential Probiotic Candidate through in vitro Assessment and Principal Component Analysis.
Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 50 citations in OpenAlex.
- Multiple Probiotic Lactic Acid Bacteria with Marked Cholesterol-Lowering Effects Were Discovered in Equine Colostrum.International journal of molecular sciences · 2026Article
- Riboflavin production by lactic acid bacteria: a mini-review.World journal of microbiology & biotechnology · 2026Review
- A sapropel-derivedFrontiers in microbiology · 2026Article
- Characterization of Lactiplantibacillus plantarum strains isolated from Algerian fruits for probiotic and biotechnological applications.Antonie van Leeuwenhoek · 2025Article
- Antibacterial Activity, Probiotic Potential, and Biocontrol Efficacy of Two Lactic Acid Bacteria AgainstFoods (Basel, Switzerland) · 2025Article
- In Vitro Screening of Bacterial Isolates From Dairy Products for Probiotic Properties and Other Health-Promoting Attributes.Food science & nutrition · 2024Article
- Microencapsulation of riboflavin-producing Lactiplantibacillus Plantarum MTCC 25,432 and Evaluation of its Survival in Simulated Gastric and Intestinal Fluid.Probiotics and antimicrobial proteins · 2024Article
- Prevalence of antibiotic resistance in lactic acid bacteria isolated from traditional fermented Indian food products.Food science and biotechnology · 2023Article
- Complete genome sequence ofMicrobiology resource announcements · 2023Article
- Biofilm formation in food processing plants and novel control strategies to combat resistant biofilms: the case ofFood science and biotechnology · 2023Review
- Functional Characterization of Lactobacillus plantarum Isolated from Cow Milk and the Development of Fermented Coconut and Carrot Juice Mixed Beverage.Current microbiology · 2023Article
- Exploration of probiotic attributes in lactic acid bacteria isolated from fermentedFrontiers in microbiology · 2023Article
- Strategies for the Identification and Assessment of Bacterial Strains with Specific Probiotic Traits.Microorganisms · 2022Review
- Probiotic assessment and antioxidant characterization ofFrontiers in microbiology · 2022Article
- A statistical optimization by response surface methodology for the enhanced production of riboflavin fromFrontiers in microbiology · 2022Article
- In Vitro Evaluation of Probiotic Properties of Lactobacillus plantarum UBLP40 Isolated from Traditional Indigenous Fermented Food.Probiotics and antimicrobial proteins · 2021Article
- Conjugal Transfer of Antibiotic Resistances in Lactobacillus spp.Current microbiology · 2021Review
- Identification of Bile Salt Hydrolase and Bile Salt Resistance in a Probiotic BacteriumMicroorganisms · 2021Article
- Article
- Vitamin B12 biofortification of soymilk through optimized fermentation with extracellular B12 producingCurrent research in food science · 2021Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactic acid bacteria (LAB) are known for their probiotic properties, but only a few strains produce riboflavin. We evaluated the probiotic properties of four riboflavin-producing strains of Lactobacillus plantarum (BBC33, BBC32A, BIF43, and BBC32B) by using in vitro assessment and carried out multivariate principal component analysis (PCA) to select the best strain. Safety, antioxidant, and exopolysaccharide-producing properties were also studied. Lact. plantarum BBC33 showed better probiotic potential, followed by strain BIF43. Lact. plantarum BBC32A degraded mucin and excluded as a potential probiotic candidate. Lact. plantarum BIF43, BBC33, and BBC32A tolerated simulated gastrointestinal conditions and their overnight cell-free culture supernatants (CFSs, pH 4.0-4.3) inhibited the growth of Escherichia coli AF10, Salmonella Typhi MTCC98, Bacillus cereus NCDC250, and Pseudomonas aeruginosa NCDC105. Lact. plantarum BIF43 and BBC33 did not degrade mucin, adhered to human epithelial colorectal adenocarcinoma Caco-2 cells (22-25%), and aggregated with indicators (30-50%). Moreover, both were non-hemolytic and sensitive to most antibiotics tested. Of the two selected strains, BIF43 showed better exopolysaccharides (EPS) producing phenotype. The CFSs of all strains showed high (85-93%) 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. PCA confirmed the results obtained from in vitro probiotic experiments and supported the selection of Lact. plantarum BIF33 and BBC43, as potential probiotics.
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