Evidence map›Paper›PMID 32808140›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021

Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study.

S S Skuladottir, A Ramel, I Hjaltadottir, L J Launer, M F Cotch, K Siggeirsdottir, V Gudnason, G Sigurdsson, L Steingrimsdottir, T Halldorsson

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

S S SkuladottirThe Icelandic Gerontological Research Institute, Tungata 5, 101, Reykjavik, Iceland. sigrunsskula@gmail.com.ORCID http://orcid.org/0000-0002-0178-974X
A RamelThe Icelandic Gerontological Research Institute, Tungata 5, 101, Reykjavik, Iceland.
I HjaltadottirLandspitali National University Hospital of Iceland, Reykjavik, Iceland.
L J LaunerLaboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MA, USA.
M F CotchDivision of Epidemiology and Clinical Applications, Intramural Research Program, National Eye Institute, National Institutes of Health, Bethesda, MA, USA.
K SiggeirsdottirIcelandic Heart Association Research Institute, Kopavogur, Iceland.
V GudnasonLandspitali National University Hospital of Iceland, Reykjavik, Iceland.
G SigurdssonLandspitali National University Hospital of Iceland, Reykjavik, Iceland.
L SteingrimsdottirFaculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland.
T HalldorssonFaculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland.
University of Iceland · ISNational Institutes of Health · USNational University Hospital of Iceland · ISIcelandic Heart Association · IS

Funding

Age, Gene/environment Susceptibility Study In Iceland - Ocular ComponentZIAEY000401 · NEI · NATIONAL EYE INSTITUTE · PI COTCH, MARY FRANCES · 2009 to 2020
$3.3M
Age, Gene/Environment Susceptibility StudyZ01AG007380 · NIA · NATIONAL INSTITUTE ON AGING · PI HARRIS, TAMARA B. · 2006 to 2008
$1.3M
AGES STUDY-THE REYKJAVIK STUDY OF HEALTHY AGING FOR THE NEW MILLENNIUM-26012100N01AG012100 · NIA · ICELANDIC HEART ASSOCIATION · 2002 to 2004
–
CEREBRAL CHEMISTRY IN DEMENTIA AND AGING--TREATMENTSZ01AG000401 · NIA · AGING · PI SHETTY, H U · 1994 to 1998
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Foundation for the National Institutes of Health N01-AG-12100Intramural NIH HHS Z01 AG007380Intramural NIH HHS ZIA EY000401National Institute on Aging Intramural Research Program, the National Eye Institute USA ZIAEY000401NIA NIH HHS N01 AG012100
6 · The paper itself

Abstract

Poor physical function and body composition my partly predict the risk of falls leading to fracture regardless of bone mineral density.

introductionTo examine the relationship between body composition, physical function, and other markers of health with hip fractures in older community-dwelling Icelandic adults.

methodsA prospective cohort of 4782 older adults from the AGES-Reykjavik study. Baseline recruitment took place between 2002 and 2006, and information on hip fractures occurring through 2012 was extracted from clinical records. Using multivariate regression analyses, baseline measures of bone health, physical function, and body composition were compared between those who later experienced hip fractures and to those who did not. Associations with the risk of fractures were quantified using Cox regression.

resultsMean age was 76.3 years at baseline. After adjustment for age, regression showed that male hip fracture cases compared with non-cases had (mean (95% confidence interval)) significantly lower thigh muscle cross-sectional area - 5.6 cm

conclusionsAfter accounting for age and BMD, older adults who later experienced a hip fracture had poorer baseline measures of physical function and/or body composition, which may at least partly contribute to the risk of falls leading to fracture.

Indexed as

Hip FracturesPostural BalanceAgedBone DensityFemaleHumansIcelandIncidenceMaleProspective StudiesRisk FactorsTime and Motion StudiesAgingBiomarkersBody compositionHip fracturePhysical function

Identifiers

PMID32808140
PMCPMC11190885
OpenAlexW3068515956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.