Evidence map›Paper›PMID 32808048›Full record

ArticleBioprocess and biosystems engineering2021

Development of a dual specific growth rate-based fed-batch process for production of recombinant human granulocyte colony-stimulating factor in Pichia pastoris.

Ashwani Gautam, Vikram Sahai, Saroj Mishra

Abstract read
PubMed Publisher
In one paragraph

Article in Bioprocess and biosystems engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Systematic optimization ofEngineering microbiology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. The advent of plant cells in bioreactors.Frontiers in plant science · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ashwani GautamCenter for Rural Development and Technology, Indian Institute of Technology Delhi, Hauz-Khas, New Delhi, 110016, India.
Vikram SahaiCare Pro Biosciences Pvt. Ltd., I - 059, Site 5, Kasna Ind Area, Gautam Buddh Nagar, Greater Noida, UP, 201308, India.
Saroj MishraDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Hauz-Khas, New Delhi, 110016, India. saroj98@hotmail.com.
Indian Institute of Technology Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of limitations exist for production of human granulocyte colony-stimulating factor (G-CSF) in Pichia pastoris. In this study, two different specific growth rates (0.015 h

Indexed as

Batch Cell Culture TechniquesGranulocyte Colony-Stimulating FactorHumansRecombinant ProteinsSaccharomycetalesGranulocyte Colony-Stimulating FactorRecombinant ProteinsFeeding strategyGranulocyte colony-stimulating factorMixed feedPichia pastorisSpecific growth rate

Identifiers

PMID32808048
OpenAlexW3059953800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.