Evidence map›Paper›PMID 32807842›Full record

ArticleScientific reports2020

High levels of ubidecarenone (oxidized CoQ

Jiaxin Sun, Chirag B Patel, Taichang Jang, Milton Merchant, Chen Chen, Shiva Kazerounian, Anne R Diers, Michael A Kiebish, Vivek K Vishnudas, Stephane Gesta and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. BPM31510 Increases the CoQ Pool in Chemically Induced CoQ-Deficient Cells, CoQ-Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cancer pharmacoinformatics: Databases and analytical tools.Functional & integrative genomics · 2024
    Review
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  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Jiaxin SunDepartment of Neurology and Clinical Neurosciences, Stanford University, Palo Alto, CA, 94305, USA. JIAXSUN@STANFORD.EDU.
Chirag B PatelDepartment of Neurology and Clinical Neurosciences, Stanford University, Palo Alto, CA, 94305, USA.
Taichang JangDepartment of Neurology and Clinical Neurosciences, Stanford University, Palo Alto, CA, 94305, USA.
Milton MerchantDepartment of Neurology and Clinical Neurosciences, Stanford University, Palo Alto, CA, 94305, USA.
Chen ChenDepartment of Otolaryngology, Stanford University, Palo Alto, CA, 94305, USA.
Shiva KazerounianBERG LLC, Framingham, MA, 01701, USA.
Anne R DiersBERG LLC, Framingham, MA, 01701, USA.
Michael A KiebishBERG LLC, Framingham, MA, 01701, USA.
Vivek K VishnudasBERG LLC, Framingham, MA, 01701, USA.
Stephane GestaBERG LLC, Framingham, MA, 01701, USA.
Rangaprasad SarangarajanBERG LLC, Framingham, MA, 01701, USA.
Niven R NarainBERG LLC, Framingham, MA, 01701, USA.
Seema NagpalDepartment of Neurology and Clinical Neurosciences, Stanford University, Palo Alto, CA, 94305, USA.
Lawrence RechtDepartment of Neurology and Clinical Neurosciences, Stanford University, Palo Alto, CA, 94305, USA. LRECHT@STANFORD.EDU.
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic reprogramming in cancer cells, vs. non-cancer cells, elevates levels of reactive oxygen species (ROS) leading to higher oxidative stress. The elevated ROS levels suggest a vulnerability to excess prooxidant loads leading to selective cell death, a therapeutically exploitable difference. Co-enzyme Q

Indexed as

Drug Delivery SystemsAnimalsCell Cycle CheckpointsCell Line, TumorCell ProliferationFemaleGliomaHumansLipidsMiceNanoparticlesNIH 3T3 CellsOxidation-ReductionPharmaceutical PreparationsRats, WistarSuperoxidescoenzyme Q10LipidsPharmaceutical PreparationsSuperoxidesUbiquinone

Identifiers

PMID32807842
PMCPMC7431533
OpenAlexW3049446842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.