Evidence map›Paper›PMID 32807479›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2020

Predictors and prognoses of new onset post-stroke anxiety at one year in black Africans.

Akin Ojagbemi, Joshua Akinyemi, Mayowa Owolabi, Rufus Akinyemi, Oyedunni Arulogun, Mulugeta Gebregziabher, Onoja Akpa, Olanrewaju Olaniyan, Babatunde Salako, Bruce Ovbiagele

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Akin OjagbemiDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria. Electronic address: aa.ojagbemi@ui.edu.ng.
Joshua AkinyemiDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria.
Mayowa OwolabiDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria.
Rufus AkinyemiDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria.
Oyedunni ArulogunDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria.
Mulugeta GebregziabherMedical University of South Carolina, United States.
Onoja AkpaDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria.
Olanrewaju OlaniyanUniversity of Ibadan, Nigeria.
Babatunde SalakoDepartment of Psychiatry, College of Medicine, University of Ibadan, Nigeria.
Bruce OvbiageleUniversity of California San Francisco, United States.
University of Ibadan · NGMedical University of South Carolina · USUniversity of California, San Francisco · US

Funding

Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THU01NS079179 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OVBIAGELE, BRUCE · 2012 to 2016
$2.1M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
NINDS NIH HHS R01 NS107900NINDS NIH HHS U01 NS079179
6 · The paper itself

Abstract

backgroundThere is relatively limited information on the risk factors and outcome of new onset Poststroke Anxiety (PSA) in Low- and Middle-Income Countries. We estimated incidence, cumulative incidence, risk factors and outcome of new onset anxiety in the first year of stroke among African stroke survivors.

methodsWe analyzed the dataset of a completed clinical trial comprising patients enrolled to test an intervention designed to improve one-year blood pressure control among recent (≤ one month) stroke survivors in Nigeria. Anxiety was measured using the Hospital Anxiety and Depression Scale. Outcomes were assessed using the modified Rankin Scale (mRS), Community screening instrument for dementia (CSID) and Health Related Quality of Life in Stroke Patients (HRQOLISP-26).

resultsAmong 322 stroke survivors who were free of anxiety at baseline, we found a one-year cumulative incidence of 34% (95% CI = 28.6-39.3). Rates were 36.2% (95% CI =29.6-42.7) for men and 29.2% (95% CI =19.9-38.3) for women. In multivariate Cox regression analyses, haemorrhagic stroke type was associated with higher risk of new onset PSA (Hazard Ratio=1.52, 95% CI =1.01-2.29). New onset PSA was independently associated with cognitive [(mean difference (MD) in CSID scores=1.1, 95% C.I=0.2, 1.9)] and motor decline (MD in mRS scores= -0.2, 95% C.I= -0.4, -0.02), as well as poorer quality of life overtime (MD in total HRQOLISP-26 scores=3.6, 95% C.I=1.0, 6.2).

conclusionOne in 3 stroke survivors in Nigeria had PSA at one year. Clinicians in SSA should pay special attention to survivors of haemorrhagic stroke as they are at higher risk of incident anxiety and therefore its consequences.

Indexed as

AgedAnxietyBlack PeopleCognitionDisability EvaluationEmotionsFemaleHumansIncidenceIntracranial HemorrhagesMaleMiddle AgedMotor ActivityNigeriaPrognosisQuality of Lifecohort studiesMental health complicationsPoststroke emotional disturbancesStroke burdenStroke outcomes

Identifiers

PMID32807479
PMCPMC7673258
OpenAlexW3040483971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.