Evidence map›Paper›PMID 32807250›Full record

ArticleBJPsych open2020

Premigration social adversity and autism spectrum disorder.

Natacha Augereau, Ines Lagdas, Solenn Kermarrec, Ludovic Gicquel, Virginie Martin, Jean Xavier, David Cohen, Michel Bouvet, Anne-Catherine Rolland, Sylvie Tordjman

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Developmental disorders among Norwegian-born children with immigrant parents.Child and adolescent psychiatry and mental health · 2023
    Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Natacha AugereauPôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Rennes (PHUPEA), Centre Hospitalier Guillaume Régnier (CHGR) and Université de Rennes 1, France.
Ines LagdasSchool of Medicine of Rabat, University of Rabat, Marrocco; and PHUPEA, CHGR and Université de Rennes 1, France.
Solenn KermarrecPHUPEA, CHGR and Université de Rennes 1, France.ORCID https://orcid.org/0000-0003-1216-8858
Ludovic GicquelPôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Centre Hospitalier Henri Laborit and Université de Poitiers, Unité de Recherche Clinique, CAPS, Poitiers, France.
Virginie MartinPôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Centre Hospitalier Henri Laborit; and Université de Poitiers, Unité de Recherche Clinique, CAPS, France.
Jean XavierCentre Hospitalier Spécialisé Henri Laborit, Poitiers; and CNRS UMR 7295 Centre de Recherches sur la Cognition et l'Apprentissage, Poitiers, France.
David CohenDepartment of Child and Adolescent Psychiatry, AP-HP, GH Pitié-Salpétrière, CNRS FRE 2987, University Pierre and Marie Curie, France.
Michel BouvetService Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Reims, Pôle Femme-Parents-Enfant, France.
Anne-Catherine RollandService Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Reims, Pôle Femme-Parents-Enfant, France.
Sylvie TordjmanPôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent (PHUPEA), Centre Hospitalier Guillaume Régnier (CHGR) and Université de Rennes 1; and Integrative Neuroscience and Cognition Center (INCC), CNRS UMR 8002 and Université de Paris, France.ORCID https://orcid.org/0000-0002-9640-7627
Centre Hospitalier Guillaume Régnier · FRCentre National de la Recherche Scientifique · FRCentre Hospitalier Universitaire de Reims · FRUniversité de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies suggest significant relationships between migration and autism spectrum disorder (ASD) but there are discrepant results. Given that no studies to date have included a pathological control group, the specificity of the results in ASD can be questioned.

aimsTo compare the migration experience (premigration, migratory trip, postmigration) in ASD and non-ASD pathological control groups, and study the relationships between migration and autism severity.

methodParents' and grandparents' migrant status was compared in 30 prepubertal boys with ASD and 30 prepubertal boys without ASD but with language disorders, using a questionnaire including Human Development Index (HDI)/Inequality-adjusted Human Development Index (IHDI) of native countries. Autism severity was assessed using the Child Autism Rating Scale, Autism Diagnostic Observation Schedule and Autism Diagnostic Interview-Revised scales.

resultsThe parents' and grandparents' migrant status frequency did not differ between ASD and control groups and was not associated with autism severity. The HDI/IHDI values of native countries were significantly lower for parents and grandparents of children with ASD compared with the controls, especially for paternal grandparents. Furthermore, HDI/IDHI levels from the paternal line (father and especially paternal grandparents) were significantly negatively correlated with autism severity, particularly for social interaction impairments.

conclusionsIn this study, parents' and/or grandparents' migrant status did not discriminate ASD and pathological control groups and did not contribute either to autism severity. However, the HDI/IHDI results suggest that social adversity-related stress experienced in native countries, especially by paternal grandparents, is potentially a traumatic experience that may play a role in ASD development. A 'premigration theory of autism' is then proposed.

Indexed as

Autism spectrum disorder (ASD)human development index (HDI/IHDI)migrationpremigration stresssocial adversity

Identifiers

PMID32807250
PMCPMC7453802
OpenAlexW3068165468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.