Evidence map›Paper›PMID 32807177›Full record

Observational studyReproductive health2020

Uptake of long acting reversible contraception following integrated couples HIV and fertility goal-based family planning counselling in Catholic and non-Catholic, urban and rural government health centers in Kigali, Rwanda.

Jeannine Mukamuyango, Rosine Ingabire, Rachel Parker, Julien Nyombayire, Andrew Abaasa, Gershim Asiki, Sarah Rae Easter, Kristin M Wall, Laetitia Nyirazinyoye, Amanda Tichacek and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Reproductive health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Jeannine MukamuyangoProjet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.
Rosine IngabireProjet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.
Rachel ParkerRwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Julien NyombayireProjet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.
Andrew AbaasaLondon School of Hygiene & Tropical Medicine (LSHTM), Keppel Street, London, WC1E 7HT, UK.
Gershim AsikiMedical Research Council, Uganda Vaccine Research Institute & LSHTM Uganda Research Unit, Entebbe, Uganda.
Sarah Rae EasterDepartment of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kristin M WallDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Laetitia NyirazinyoyeUniversity of Rwanda School of Public Health, Kigali, Rwanda.
Amanda TichacekRwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Nadine KaslowDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, GA, USA.
Matt A PriceInternational AIDS Vaccine Initiative, New York, NY, USA.
Susan AllenRwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, USA. sallen5@emory.edu.ORCID http://orcid.org/0000-0002-9150-3898
Etienne KaritaProjet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.
Emory University · USRwanda Zambia HIV Research Group · RWBrigham and Women's Hospital · USInternational AIDS Vaccine Initiative · USUganda Virus Research Institute · UGUniversity of London · GBUniversity of Rwanda · RW

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
EMORY AIDS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW001042 · FIC · EMORY UNIVERSITY · PI DEL RIO, CARLOS · 1998 to 2013
$6.8M
Couples HIV Counseling &Testing in two African capitalsR01MH066767 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLEN, SUSAN A · 2002 to 2006
$6.1M
Family Planning Promotion in HIV Infected ZambiansR01HD040125 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLEN, SUSAN A. · 2001 to 2005
$4.2M
Int'l Traineeships in AIDS Prevention Studies (ITAPS)R25MH064712 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINDAN, CHRISTINA P · 2002 to 2018
$3.4M
VCT with Primary and Concurrent Partners to Prevent HIV Transmission R01MH095503 · NIMH · EMORY UNIVERSITY · PI ALLEN, SUSAN A · 2011 to 2016
$2.5M
International Traineeships in AIDS Prevention Studies (ITAPS)R25MH123256 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTINA P LINDAN · 2020 to 2026
$1.8M
FIC NIH HHS D43 TW001042NIAID NIH HHS P30 AI050409NICHD NIH HHS R01 HD040125NIMH NIH HHS K01_MH10730NIMH NIH HHS MH66767NIMH NIH HHS MH95503NIMH NIH HHS R01 MH066767NIMH NIH HHS R01 MH095503NIMH NIH HHS R25 MH064712NIMH NIH HHS R25 MH123256
6 · The paper itself

Abstract

backgroundWhen integrated with couples' voluntary HIV counselling and testing (CVCT), family planning including long acting reversible contraceptives (LARC) addresses prongs one and two of prevention of mother-to-child transmission (PMTCT).

methodsIn this observational study, we enrolled equal numbers of HIV concordant and discordant couples in four rural and four urban clinics, with two Catholic and two non-Catholic clinics in each area. Eligible couples were fertile, not already using a LARC method, and wished to limit or delay fertility for at least 2 years. We provided CVCT and fertility goal-based family planning counselling with the offer of LARC and conducted multivariate analysis of clinic, couple, and individual predictors of LARC uptake.

resultsOf 1290 couples enrolled, 960 (74%) selected LARC: Jadelle 5-year implant (37%), Implanon 3-year implant (26%), or copper intrauterine device (IUD) (11%). Uptake was higher in non-Catholic clinics (85% vs. 63% in Catholic clinics, p < 0.0001), in urban clinics (82% vs. 67% in rural clinics, p < 0.0001), and in HIV concordant couples (79% vs. 70% of discordant couples, p = .0005). Religion of the couple was unrelated to clinic religious affiliation, and uptake was highest among Catholics (80%) and lowest among Protestants (70%) who were predominantly Pentecostal. In multivariable analysis, urban location and non-Catholic clinic affiliation, Catholic religion of woman or couple, younger age of men, lower educational level of both partners, non-use of condoms or injectable contraception at enrollment, prior discussion of LARC by the couple, and women not having concerns about negative side effects of implant were associated with LARC uptake.

conclusionsFertility goal-based LARC recommendations combined with couples' HIV counselling and testing resulted in a high uptake of LARC methods, even among discordant couples using condoms for HIV prevention, in Catholic clinics, and in rural populations. This model successfully integrates prevention of HIV and unplanned pregnancy.

Indexed as

CatholicismFertilityAdultAnti-Retroviral AgentsContraceptionCounselingDelivery of Health Care, IntegratedFamily CharacteristicsFamily Planning ServicesFemaleGoalsGovernmentHIV InfectionsHumansInfectious Disease Transmission, VerticalLong-Acting Reversible ContraceptionAnti-Retroviral Agents

Identifiers

PMID32807177
PMCPMC7433361
OpenAlexW3075318819

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.