Evidence map›Paper›PMID 32806870›Full record

ArticleIntestinal research2020

Phenotypic characteristics of pediatric inflammatory bowel disease in Japan: results from a multicenter registry.

Katsuhiro Arai, Reiko Kunisaki, Fumihiko Kakuta, Shin-Ichiro Hagiwara, Takatsugu Murakoshi, Tadahiro Yanagi, Toshiaki Shimizu, Sawako Kato, Takashi Ishige, Tomoki Aomatsu and 14 more

Open access · diamondAbstract read
In one paragraph

Article in Intestinal research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

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  8. Inflammatory Bowel Disease in Jordanian Children: A Tertiary Center Experience.Pediatric gastroenterology, hepatology & nutrition · 2025
    Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 1 country.

Katsuhiro AraiDivision of Gastroenterology, National Center for Child Health and Development, Setagaya, Japan.
Reiko KunisakiInflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, Japan.
Fumihiko KakutaDepartment of General Pediatrics and Gastroenterology, Miyagi Children's Hospital, Sendai, Japan.
Shin-Ichiro HagiwaraDivision of Gastroenterology and Hepatology, Saitama Children's Medical Center, Saitama, Japan.
Takatsugu MurakoshiDepartment of Gastroenterology, Tokyo Metropolitan Children's Medical Center, Fuchu, Japan.
Tadahiro YanagiDepartment of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Japan.
Toshiaki ShimizuDepartment of Pediatric and Adolescent Medicine, Juntendo University Graduate School of Medicine, Bunkyo, Japan.
Sawako KatoDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Takashi IshigeDepartment of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Japan.
Tomoki AomatsuDepartment of Pediatrics, Osaka Medical College, Takatsuki, Japan.
Mikihiro InoueDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Takeshi SaitoDepartment of Pediatric Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Itaru IwamaDepartment of Pediatrics, Okinawa Prefectural Chubu Hospital, Okinawa, Japan.
Hisashi KawashimaDepartment of Pediatrics, Tokyo Medical University, Shinjuku, Japan.
Hideki KumagaiDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Hitoshi TajiriDepartment of Pediatrics, Osaka General Medical Center, Osaka, Japan.
Naomi IwataDivision of Infectious Disease and Immunology, Aichi Children's Health and Medical Center, Obu, Japan.
Takahiro MochizukiDepartment of Pediatrics, Osaka Police Hospital, Osaka, Japan.
Atsuko NoguchiDepartment of Pediatrics, Akita University Graduate School of Medicine, Akita, Japan.
Toshihiko KashiwabaraDepartment of Gastroenterology, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Hirotaka ShimizuDivision of Gastroenterology, National Center for Child Health and Development, Setagaya, Japan.
Yasuo SuzukiInflammatory Bowel Disease Center, Toho University Sakura Medical Center, Sakura, Japan.
Yuri HiranoDivision of Gastroenterology, National Center for Child Health and Development, Setagaya, Japan.
Takeo FujiwaraDepartment of Global Health Promotion, Tokyo Medical and Dental University, Bunkyo, Japan.
National Center For Child Health and Development · JPAkita University · JPChiba University · JPGunma University · JPJichi Medical University · JPJuntendo University · JPKurume University · JPMie University · JPMiyagi Children's Hospital · JPOkinawa Prefectural Chubu Hospital · JPOsaka Medical and Pharmaceutical University · JPOsaka Police Hospital · JPOsaka Prefectural Medical Center · JPSaitama Children's Medical Center · JPShinshu University · JPToho University · JPTokyo Medical and Dental University · JPTokyo Medical University · JPTokyo Metropolitan Children's Medical Center · JPYamagata Prefectural Central Hospital · JP

Funding

Ministry of Health, Labour and WelfareNational Center for Child Health and Development
6 · The paper itself

Abstract

BACKGROUND/

aimsThere are few published registry studies from Asia on pediatric inflammatory bowel disease (IBD). Registry network data enable comparisons among ethnic groups. This study examined the characteristics of IBD in Japanese children and compared them with those in European children.

methodsThis was a cross-sectional multicenter registry study of newly diagnosed Japanese pediatric IBD patients. The Paris classification was used to categorize IBD features, and results were compared with published EUROKIDS data.

resultsA total of 265 pediatric IBD patients were initially registered, with 22 later excluded for having incomplete demographic data. For the analysis, 91 Crohn's disease (CD), 146 ulcerative colitis (UC), and 6 IBD-unclassified cases were eligible. For age at diagnosis, 20.9% of CD, 21.9% of UC, and 83.3% of IBD-unclassified cases were diagnosed before age 10 years. For CD location, 18.7%, 13.2%, 64.8%, 47.3%, and 20.9% were classified as involving L1 (ileocecum), L2 (colon), L3 (ileocolon), L4a (esophagus/stomach/duodenum), and L4b (jejunum/proximal ileum), respectively. For UC extent, 76% were classified as E4 (pancolitis). For CD behavior, B1 (non-stricturing/non-penetrating), B2 (stricturing), B3 (penetrating), and B2B3 were seen in 83.5%, 11.0%, 3.3%, and 2.2%, respectively. A comparison between Japanese and European children showed less L2 involvement (13.2% vs. 27.3%, P< 0.01) but more L4a (47.3% vs. 29.6%, P< 0.01) and L3 (64.8% vs. 52.7%, P< 0.05) involvement in Japanese CD children. Pediatric perianal CD was more prevalent in Japanese children (34.1% vs. 9.7%, P< 0.01).

conclusionsUpper gastrointestinal and perianal CD lesions are more common in Japanese children than in European children.

Indexed as

ChildrenInflammatory bowel diseaseJapanPerianal Crohn diseaseRegistry

Identifiers

PMID32806870
PMCPMC7609396
OpenAlexW3073301309

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.