Evidence map›Paper›PMID 32806773›Full record

ReviewCells2020

Human Neural Stem Cell Systems to Explore Pathogen-Related Neurodevelopmental and Neurodegenerative Disorders.

Matteo Baggiani, Maria Teresa Dell'Anno, Mauro Pistello, Luciano Conti, Marco Onorati

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Matteo BaggianiUnit of Cell and Developmental Biology, Department of Biology, University of Pisa, 56126 Pisa, Italy.
Maria Teresa Dell'AnnoCellular Engineering Laboratory, Fondazione Pisana per la Scienza ONLUS, 56017 Pisa, Italy.
Mauro PistelloRetrovirus Center and Virology Section, Department of Translational Research, University of Pisa and Virology Division, Pisa University Hospital, 56100 Pisa, Italy.
Luciano ContiDepartment of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, 38122 Trento, Italy.ORCID 0000-0002-2050-9846
Marco OnoratiUnit of Cell and Developmental Biology, Department of Biology, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-8517-930X
University of Pisa · ITFondazione Pisa · ITUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Building and functioning of the human brain requires the precise orchestration and execution of myriad molecular and cellular processes, across a multitude of cell types and over an extended period of time. Dysregulation of these processes affects structure and function of the brain and can lead to neurodevelopmental, neurological, or psychiatric disorders. Multiple environmental stimuli affect neural stem cells (NSCs) at several levels, thus impairing the normal human neurodevelopmental program. In this review article, we will delineate the main mechanisms of infection adopted by several neurotropic pathogens, and the selective NSC vulnerability. In particular, TORCH agents, i.e.,

Indexed as

Alzheimer DiseaseAnimalsDNA VirusesDNA Virus InfectionsHost-Pathogen InteractionsHumansMiceMicrocephalyNeural Stem CellsNeurodevelopmental DisordersRNA VirusesRNA Virus InfectionsToxoplasmaToxoplasmosisVirulenceAlzheimer’s diseasehuman neural stem cellsmicrocephalyneurodegenerationneurodevelopmentTORCH syndrome

Identifiers

PMID32806773
PMCPMC7464299
OpenAlexW3048890195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.