Evidence map›Paper›PMID 32806755›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

Gold Nanoparticles: A New Golden Era in Oncology?

Clara Gerosa, Guido Crisponi, Valeria Marina Nurchi, Luca Saba, Rosita Cappai, Flaviana Cau, Gavino Faa, Peter Van Eyken, Mario Scartozzi, Giuseppe Floris and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  4. Article
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  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Clara GerosaUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, Italy.
Guido CrisponiDipartimento di Scienze della Vita e dell'Ambiente, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-3902-0231
Valeria Marina NurchiDipartimento di Scienze della Vita e dell'Ambiente, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-4004-1988
Luca SabaUOC Radiologia, AOU Cagliari, University of Cagliari, 09042 Cagliari, Italy.
Rosita CappaiDipartimento di Scienze della Vita e dell'Ambiente, University of Cagliari, 09042 Cagliari, Italy.
Flaviana CauUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, Italy.
Gavino FaaUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, Italy.
Peter Van EykenDepartment of Pathology, Genk Regional Ziekenhuis, 3600 Genk, Belgium.
Mario ScartozziUOC Oncologia Medica, AOU Cagliari, University of Cagliari, 09042 Cagliari, Italy.
Giuseppe FlorisPathologische Ontleedkunde K.U. Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-2391-5425
Daniela FanniUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, Italy.
University of Cagliari · ITKU Leuven · BEZiekenhuis Oost-Limburg · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the spectrum of possible applications of gold in diagnostics and therapeutic approaches in clinical practice has changed significantly, becoming surprisingly broad. Nowadays, gold-based therapeutic agents are used in the therapy of multiple human diseases, ranging from degenerative to infectious diseases and, in particular, to cancer. At the basis of these performances of gold, there is the development of new gold-based nanoparticles, characterized by a promising risk/benefit ratio that favors their introduction in clinical trials. Gold nanoparticles appear as attractive elements in nanomedicine, a branch of modern clinical medicine, which combines high selectivity in targeting tumor cells and low toxicity. Thanks to these peculiar characteristics, gold nanoparticles appear as the starting point for the development of new gold-based therapeutic strategies in oncology. Here, the new gold-based therapeutic agents developed in recent years are described, with particular emphasis on the possible applications in clinical practice as anticancer agents, with the aim that their application will give rise to a new golden age in oncology and a breakthrough in the fight against cancer.

Indexed as

goldnanoparticlesoncology

Identifiers

PMID32806755
PMCPMC7464886
OpenAlexW3048458860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.