Evidence map›Paper›PMID 32806734›Full record

ReviewInternational journal of environmental research and public health2020

Insights from Experiences on Antiplatelet Drugs in Stroke Prevention: A Review.

Salvatore Santo Signorelli, Ingrid Platania, Salvatore Davide Tomasello, Marco Mangiafico, Giuliana Barcellona, Domenico Di Raimondo, Agostino Gaudio

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. New Insights in Prevention and Treatment of Cardiovascular Disease.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Salvatore Santo SignorelliDepartment of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.ORCID 0000-0001-9264-0061
Ingrid PlataniaGeneral Medicine Division, University Hospital G. Rodolico, 95123 Catania, Italy.
Salvatore Davide TomaselloDivision of Hemodynamic and Interventional Cardiology, Hospital Cannizzaro, 95123 Catania, Italy.
Marco MangiaficoDepartment of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Giuliana BarcellonaDepartment of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Domenico Di RaimondoDivision of Internal Medicine and Stroke Care, Department of Promoting Health, Maternal-Infant, Excellence and Internal and Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-4529-3703
Agostino GaudioDepartment of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-9958-9606
University of Catania · ITOspedale Cannizzaro · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduction of hazard risk of cerebral ischemic event (stroke, transient ischemic attack (TIA)) represents the hard point to be achieved from primary or secondary preventive strategy in the best clinical practice. However, results from clinical trials, recommendations, guidelines, systematic review, expert opinions, and meta-analysis debated on the optimal pharmacotherapy to achieve the objective. Aspirin and a number of antiplatelet agents, alone or in combination, have been considered from large trials focused on stroke prevention. The present review summarizes, discusses results from trials, and focuses on the benefits or disadvantages originating from antiplatelet drugs. Sections of the review were organized to show both benefits or consequences from antiplatelet pharmacotherapy. Conclusively, this review provides a potential synopsis on the most appropriate therapeutic approach for stroke prevention in clinical practice.

Indexed as

Diabetes Mellitus, Type 2Ischemic Attack, TransientPlatelet Aggregation InhibitorsStrokeAgedDouble-Blind MethodDrug Therapy, CombinationFemaleHumansMaleMiddle AgedSecondary PreventionPlatelet Aggregation Inhibitorsaspirincilostazolclopidogrelcombined drug therapydipyridamolepreventionstroke

Identifiers

PMID32806734
PMCPMC7460138
OpenAlexW3048569015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.