Evidence map›Paper›PMID 32806730›Full record

ArticleJournal of clinical medicine2020

Characterization of IgA Deposition in the Kidney of Patients with IgA Nephropathy and Minimal Change.

Won-Hee Cho, Seon-Hwa Park, Seul-Ki Choi, Su Woong Jung, Kyung Hwan Jeong, Yang-Gyun Kim, Ju-Young Moon, Sung-Jig Lim, Ji-Youn Sung, Jong Hyun Jhee and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Won-Hee ChoDepartment of Medicine, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Seon-Hwa ParkDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.
Seul-Ki ChoiDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.
Su Woong JungDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.
Kyung Hwan JeongDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Medical Center, Seoul 02447, Korea.
Yang-Gyun KimDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.ORCID 0000-0002-3497-5514
Ju-Young MoonDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.
Sung-Jig LimDepartment of Pathology, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul 05278, Korea.ORCID 0000-0003-2549-8434
Ji-Youn SungDepartment of Pathology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul 02447, Korea.
Jong Hyun JheeDivision of Nephrology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.
Ho Jun ChinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea.
Bum Soon ChoiDivision of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0002-1412-9951
Sang-Ho LeeDivision of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul 05278, Korea.
Kyung Hee University Hospital at Gangdong · KRKyung Hee University · KRCatholic University of Korea · KRKyung Hee University Medical Center · KRSeoul National University · KRYonsei University · KR

Funding

the National Research Foundation of Korea by the korean government 2018M3A9E8078807
6 · The paper itself

Abstract

Approximately 5% of patients with IgA nephropathy (IgAN) exhibit mild mesangial lesions with acute onset nephrotic syndrome and diffuse foot process effacement representative of minimal change disease (MCD). It is not clear whether these unusual cases of IgAN with MCD (IgAN-MCD) are variant types of IgAN or coincidental deposition of IgA in patients with MCD. In a retrospective multicenter cohort study of 18 hospitals in Korea, we analyzed 46 patients with IgAN-MCD. Patients with endocapillary proliferation, segmental sclerosis, and crescent were excluded, and the clinical features and prognosis of IgAN-MCD were compared with those of pure MCD. In addition, we performed galactose-deficient IgA1 (KM55) staining to characterize IgAN-MCD. Among the 21,697 patients with glomerulonephritis enrolled in the database, 46 patients (0.21%) were diagnosed with IgAN-MCD, and 1610 patients (7.4%) with pure MCD. The 46 patients with IgAN-MCD accounted for 0.6% of primary IgAN patients (

Indexed as

double immunofluorescent staininggalactose-deficient IgA1IgA nephropathy with minimal change diseaseKM55nephrotic syndrome

Identifiers

PMID32806730
PMCPMC7464421
OpenAlexW3048518036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.