Evidence map›Paper›PMID 32806718›Full record

SynthesisNutrients2020

Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials.

Chun-De Liao, Yen-Tzu Wu, Jau-Yih Tsauo, Pey-Rong Chen, Yu-Kang Tu, Hung-Chou Chen, Tsan-Hon Liou

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chun-De LiaoSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei 100025, Taiwan.ORCID 0000-0002-1930-4915
Yen-Tzu WuSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei 100025, Taiwan.ORCID 0000-0001-5035-4577
Jau-Yih TsauoSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei 100025, Taiwan.
Pey-Rong ChenDepartment of Dietetics, National Taiwan University Hospital, Taipei 100225, Taiwan.
Yu-Kang TuInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 100025, Taiwan.ORCID 0000-0002-2461-474X
Hung-Chou ChenDepartment of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235041, Taiwan.
Tsan-Hon LiouDepartment of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235041, Taiwan.ORCID 0000-0002-0959-4023
National Taiwan University · TWTaipei Medical University-Shuang Ho Hospital · TWNational Taiwan University Hospital · TW

Funding

Ministry of Science and Technology, Taiwan MOST 108-2314-B-038-102-MY3Taipei Medical University IIT-1072-3Taipei Medical University-Shuang Ho Hospital 109TMU-SHH-13
6 · The paper itself

Abstract

Aging and osteoarthritis (OA) are associated with a high risk of muscle mass loss, which can lead to physical disability. This study investigated the effectiveness of protein supplementation combined with exercise training (PS + ET) in improving muscle mass and functional outcomes in older adults with lower-limb OA. A comprehensive search of online databases was performed to identify randomized controlled trials (RCTs) on the effectiveness of PS + ET in older adults with hip or knee OA. Meta-analysis and risk of bias assessment of the included RCTs were conducted. Six RCTs were included in this systemic review; they had a median (range/total) Physiotherapy Evidence Database (PEDro) score of 7 (6-9) out of 10, respectively. Five RCTs that enrolled patients who underwent total joint replacement were included in this meta-analysis. The PS + ET group exhibited significant improvements in muscle mass (standard mean difference [SMD] = 1.13,

Indexed as

Dietary SupplementsAgedAged, 80 and overDietary ProteinsExerciseExercise TherapyFemaleHumansMaleMuscle StrengthMuscular AtrophyOsteoarthritisPhysical Functional PerformanceRandomized Controlled Trials as TopicTreatment OutcomeDietary Proteinsarthroplastyexercise trainingmuscle massosteoarthritisphysical functionprotein supplementsarcopenia

Identifiers

PMID32806718
PMCPMC7468926
OpenAlexW3048375460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.