ArticleJournal of clinical medicine2020
Sjögren's Syndrome: The Clinical Spectrum of Male Patients.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- From Molecular Pathophysiology to Clinical Trial Design in Sjögren's Disease: A Three-Axis Framework.International journal of molecular sciences · 2026Review
- Sex and gender differences in rheumatology: clinical impact and future directions.Nature reviews. Rheumatology · 2026Review
- Increased Prevalence of Extrathymic Neoplasms in Myasthenia Gravis Patients-A Population-Based, Matched Case-Control Study.Muscle & nerve · 2026Article
- Evaluation of patients diagnosed with primary Sjogren's syndrome with and without pulmonary involvement.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Premature Ischemic Stroke in Sjögren's Disease.Journal of stroke · 2025Article
- Global Trends and Insights Into the Neurological Manifestations of Sjögren's Syndrome: A Bibliometric Review.Cureus · 2025Review
- Ovarian reserve in patients with Sjögren's syndrome: a cross-sectional study.Clinical rheumatology · 2025Article
- IFN-γ-producing TScience translational medicine · 2024Article
- HLA-DR genotypes in patients with primary Sjögren's syndrome in Taiwan.The Kaohsiung journal of medical sciences · 2024Article
- Clinical Profile of Patients with Primary Sjögren's Syndrome with Non-Identified Antinuclear Autoantibodies.Diagnostics (Basel, Switzerland) · 2024Article
- Interstitial Lung Disease and Pulmonary Damage in Primary Sjögren's Syndrome: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Phenotypic and proteomic analysis of plasma extracellular vesicles highlights them as potential biomarkers of primary Sjögren syndrome.Frontiers in immunology · 2023Article
- JAK/STAT Pathway Targeting in Primary Sjögren Syndrome.Rheumatology and immunology research · 2022Review
- Regulation of MMP9 transcription by ETS1 in immortalized salivary gland epithelial cells of patients with salivary hypofunction and primary Sjögren's syndrome.Scientific reports · 2022Article
- Risk of Cancer in Connective Tissue Diseases in Northeastern Italy over 15 Years.Journal of clinical medicine · 2022Article
- Sjogren's Syndrome: Recent Updates.Journal of clinical medicine · 2022Article
- Addressing the clinical unmet needs in primary Sjögren's Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts.Computational and structural biotechnology journal · 2022Article
- Sjögren syndrome: looking forward to the future.Therapeutic advances in musculoskeletal disease · 2022Review
- A prospective multicenter study assessing humoral immunogenicity and safety of the mRNA SARS-CoV-2 vaccines in Greek patients with systemic autoimmune and autoinflammatory rheumatic diseases.Journal of autoimmunity · 2021Article
- Ten-year survival analysis of patients with primary Sjögren's syndrome in China: a national prospective cohort study.Therapeutic advances in musculoskeletal disease · 2021Article
Corrections and comments
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Authors and funding
21 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundTo compare the clinical, serological and histologic features between male and female patients with Sjögren's syndrome (SS) and explore the potential effect of gender on lymphoma development.
methodsFrom a multicenter population (Universities of Udine, Pisa and Athens, Harokopion and Ioannina (UPAHI)) consisting of consecutive SS patients fulfilling the 2016 ACR/EULAR criteria, male patients were identified, matched and compared with female controls. Data-driven multivariable logistic regression analysis was applied to identify independent lymphoma-associated factors.
resultsFrom 1987 consecutive SS patients, 96 males and 192 matched female controls were identified and compared. Males had a higher frequency of lymphoma compared to females (18% vs. 5.2%, OR = 3.89, 95% CI: 1.66 to 8.67;
conclusionMale SS patients carry an increased risk of lymphoma development. Although statistics showed no difference in classical lymphoma predictors compared to females, data-driven analysis revealed gender and lymphadenopathy as independent lymphoma-associated features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.