Evidence map›Paper›PMID 32806608›Full record

ArticleMolecules (Basel, Switzerland)2020

A New Eucalyptol-Rich Lavender (

Mohamed Nadjib Boukhatem, Thangirala Sudha, Noureldien H E Darwish, Henni Chader, Asma Belkadi, Mehdi Rajabi, Aicha Houche, Fatma Benkebailli, Faiza Oudjida, Shaker A Mousa

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 75 citations in OpenAlex.

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  5. Plants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Mohamed Nadjib BoukhatemThe Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, New York, NY 12144, USA.ORCID 0000-0002-0089-2710
Thangirala SudhaThe Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, New York, NY 12144, USA.
Noureldien H E DarwishThe Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, New York, NY 12144, USA.ORCID 0000-0002-4124-9772
Henni ChaderLaboratoire de Pharmaco-Toxicologie, Laboratoire National de Contrôle des Produits Pharmaceutiques (LNCPP), Dely-Ibrahim, Algiers 16047, Algeria.
Asma BelkadiLaboratoire Pharmaco-Toxicologie, Centre de Recherche & Développement Saidal, Algiers 16004, Algeria.
Mehdi RajabiThe Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, New York, NY 12144, USA.
Aicha HoucheDépartement de Biologie et Physiologie Celulaire, Faculté des Sciences de la Nature et de la Vie, Université-Saad Dahlab-Blida 1, Blida 09000, Algeria.
Fatma BenkebailliDépartement de Biologie et Physiologie Celulaire, Faculté des Sciences de la Nature et de la Vie, Université-Saad Dahlab-Blida 1, Blida 09000, Algeria.
Faiza OudjidaLaboratoire d'Anatomie Pathologique, Centre Hospitalo-Universitiare de Beni-Messous, Algiers 16206, Algeria.
Shaker A MousaThe Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, New York, NY 12144, USA.ORCID 0000-0002-9294-015X
Albany College of Pharmacy and Health Sciences · USUniversity of Blida · DZCentre de Recherche Nucléaire d’Alger · DZCentre Hospitalo-Universitaire Bab El Oued · DZMansoura University · EGUniversity of Algiers Benyoucef Benkhedda · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimnatural products are a potential source for drug discovery and development of cancer chemoprevention. Considering that drugs currently available for the treatment of inflammatory and cancer conditions show undesirable side effects, this research was designed to evaluate, for the first time, the in vitro anticancer activity of Algerian MATERIALS AND

methodsthe LSEO was extracted by steam distillation, and chemical composition analysis was performed using gas chromatography. The main compounds identified in LSEO were oxygenated monoterpenes, such as 1,8-Cineole (61.36%). LSEO exhibited a potent anti-inflammatory activity using the xylene-induced mouse ear edema model.

resultsLSEO (200 and 20 mg/kg) was able to significantly reduce (

conclusionWe suggest that LSEO, with 1,8-Cineole as the major active component, is a promising candidate for use in skin care products with anti-inflammatory and anticancer properties. The results of this study may provide an experimental basis for further systematic research, rational development, and clinical utilization of lavender resources.

Indexed as

Anti-Inflammatory AgentsAntineoplastic Agents, PhytogenicEucalyptolOils, VolatilePlant OilsAnimalsCell Line, TumorHumansInflammationLavandulaMiceNeoplasmsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicEucalyptollavender oilOils, VolatilePlant Oils1,8-Cineoleanticancer activityLavandula stoechas essential oilmelanoma cell linestopical anti-inflammatory effect

Identifiers

PMID32806608
PMCPMC7463424
OpenAlexW3048660216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.