Evidence map›Paper›PMID 32806507›Full record

ArticlePharmaceutics2020

Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells.

Nabil A Alhakamy, Shaimaa M Badr-Eldin, Usama A Fahmy, Nabil K Alruwaili, Zuhier A Awan, Giuseppe Caruso, Mohamed A Alfaleh, Ahmed L Alaofi, Faris O Arif, Osama A A Ahmed and 1 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Fabrication of Phytosome with Enhanced Activity ofInternational journal of nanomedicine · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. The therapeutic potential of carnosine: Focus on cellular and molecular mechanisms.Current research in pharmacology and drug discovery · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Nabil A AlhakamyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-3826-1519
Shaimaa M Badr-EldinDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Usama A FahmyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-6094-5570
Nabil K AlruwailiDepartment of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Al-Jouf 2014, Saudi Arabia.
Zuhier A AwanDepartment of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-4176-335X
Giuseppe CarusoOasi Research Institute-IRCCS, Via Conte Ruggero, 73, 94018 Troina (EN), Italy.ORCID 0000-0003-1571-5327
Mohamed A AlfalehDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-3716-0019
Ahmed L AlaofiDepartment of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Faris O ArifGeneral Surgery KAUH, King Abdulaziz University Hospital, Jeddah 21589, Saudi Arabia.
Osama A A AhmedDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-3204-381X
Adel F AlghaithDepartment of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
King Abdulaziz University · SAKing Saud University · SACairo University · EGJouf University · SAOasi Maria SS · IT

Funding

King Abdulaziz University (RG-2-166-41)
6 · The paper itself

Abstract

Thymoquinone (TQ), a natural polyphenol, has been associated with various pharmacological responses; however, low bioavailability of TQ limits its clinical application. Thus, a novel phytosomal delivery system of TQ-Phospholipon

Indexed as

apoptotic potentialbiphasic releaseBox-Behnken designcell cycle arrestcytotoxicityROS generationthymoquinone

Identifiers

PMID32806507
PMCPMC7463966
OpenAlexW3048559705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.