Evidence map›Paper›PMID 32805299›Full record

ArticleBiological psychology2020

Hair cortisol and dehydroepiandrosterone concentrations: Associations with executive function in early childhood.

Ella-Marie P Hennessey, Olga Kepinska, Stephanie L Haft, Megan Chan, Isabel Sunshine, Chloe Jones, Roeland Hancock, Fumiko Hoeft

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ella-Marie P HennesseyDepartment of Psychiatry and Weill Institute for Neurosciences and Dyslexia Center, University of California San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Multi-University Precision Learning Center, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Department of Psychology, University of Denver, 2155 S. Race Street, Denver, CO, 80210, USA.
Olga KepinskaDepartment of Psychiatry and Weill Institute for Neurosciences and Dyslexia Center, University of California San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA.
Stephanie L HaftDepartment of Psychiatry and Weill Institute for Neurosciences and Dyslexia Center, University of California San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Department of Psychology, University of California Berkeley, 2121 Berkeley Way, Berkeley, CA, 94704, USA.
Megan ChanDepartment of Psychiatry and Weill Institute for Neurosciences and Dyslexia Center, University of California San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Multi-University Precision Learning Center, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Department of Psychology, University of California Berkeley, 2121 Berkeley Way, Berkeley, CA, 94704, USA.
Isabel SunshineDepartment of Psychiatry and Weill Institute for Neurosciences and Dyslexia Center, University of California San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Multi-University Precision Learning Center, 401 Parnassus Ave., San Francisco, CA, 94143, USA.
Chloe JonesBrain Imaging Research Center (BIRC) & Department of Psychological Sciences, University of Connecticut, 850 Bolton Road, Storrs, CT, 06269, USA.
Roeland HancockBrain Imaging Research Center (BIRC) & Department of Psychological Sciences, University of Connecticut, 850 Bolton Road, Storrs, CT, 06269, USA.
Fumiko HoeftDepartment of Psychiatry and Weill Institute for Neurosciences and Dyslexia Center, University of California San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Multi-University Precision Learning Center, 401 Parnassus Ave., San Francisco, CA, 94143, USA; Brain Imaging Research Center (BIRC) & Department of Psychological Sciences, University of Connecticut, 850 Bolton Road, Storrs, CT, 06269, USA; Haskins Laboratories, 300 George St #900, New Haven, CT, 06511, USA; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi Shinjuku, Tokyo, 160-8582 Japan. Electronic address: fumiko.hoeft@uconn.edu.
University of California, San Francisco · USUniversity of Connecticut · USKeio University Hospital · JPUniversity of California, Berkeley · US

Funding

THE FLORIDA LONGITUDINAL STUDYP50HD052120 · NICHD · FLORIDA STATE UNIVERSITY · PI Nicole Sandi Patton-Terry · 2006 to 2026
$31.7M
Cognitive and Neural Processes in Reading ComprehensionR01HD044073 · NICHD · VANDERBILT UNIVERSITY · PI CUTTING, LAURIE E · 2004 to 2019
$8.1M
Neural Mechanisms Underlying Compensation in DyslexiaR01HD096261 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI HOEFT, FUMIKO · 2018 to 2023
$3.4M
Intergenerational Neuroimaging of Language and Reading Networks Using a Natural Cross-Fostering DesignR01HD094834 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI HOEFT, FUMIKO · 2019 to 2024
$3.4M
Neurochemistry as a moderator of brain networks for readingR01HD086168 · NICHD · HASKINS LABORATORIES, INC. · PI HOEFT, FUMIKO, PUGH, KENNETH R. · 2016 to 2020
$3.2M
Understanding literacy acquisition through immersion in foreign languagesR01HD078351 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HENDREN, ROBERT LEE, HOEFT, FUMIKO · 2015 to 2020
$3.0M
NICHD NIH HHS P50 HD052120NICHD NIH HHS R01 HD044073NICHD NIH HHS R01 HD078351NICHD NIH HHS R01 HD086168NICHD NIH HHS R01 HD094834NICHD NIH HHS R01 HD096261
6 · The paper itself

Abstract

Chronic stress during childhood negatively impacts cognition and physical and mental health. Exposure to stressors over time can cause hypothalamic-pituitary-adrenal (HPA) axis dysregulation, leading to abnormal stress hormone levels, which can be reflected in hair cortisol concentration (HCC) and hair dehydroepiandrosterone (DHEA) concentration. Although the use of HCC and DHEA to measure chronic stress in children is increasing, their effects on cognition (as indexed by executive function) remain unexplored. Accordingly, we aimed to investigate the associations of HCC, DHEA, and their ratio with measures of executive function (cognitive flexibility and working memory) in a sample of kindergarten children (N=100). We found that the expected negative association between HCC and working memory approached significance, and DHEA was significantly and positively related to cognitive flexibility. We discuss possible interpretations of our findings. Our results suggest promising areas for future investigation and encourage further exploration into HCC and DHEA as measures of chronic stress.

Indexed as

Executive FunctionHydrocortisoneChildChild, PreschoolDehydroepiandrosteroneHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemDehydroepiandrosteroneHydrocortisoneChildrenChronic stressCortisolDehydroepiandrosteroneExecutive function

Identifiers

PMID32805299
PMCPMC7530148
OpenAlexW3049597226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.