ReviewChest2020
It Takes a Village…: Contending With Drug Shortages During Disasters.
Review in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- When supply chains fail: rethinking resilience in intensive care.Critical care (London, England) · 2026Review
- Drug supply chain disruptions and outpatient medication shortages in the Veterans Health Administration, 2017-2020.Exploratory research in clinical and social pharmacy · 2026Article
- Adjustment of medical standards in disaster, crises and war: a scoping review of the literature.BMJ public health · 2024Article
- Managing medicine shortages.Australian prescriber · 2024Review
- Gamification in Critical Care Education and Practice.Critical care explorations · 2024Article
- Oral contraceptive pills shortage in Lebanon amidst the economic collapse: a nationwide exploratory study.BMC health services research · 2023Article
- Occurrence of Z-drugs, benzodiazepines, and ketamine in wastewater in the United States and Mexico during the Covid-19 pandemic.The Science of the total environment · 2023Article
- Review
- Implementation of supply management strategies by the pharmacy service in a general hospital during the COVID-19 pandemic.Exploratory research in clinical and social pharmacy · 2022Article
- Rapid Response to the Acute Iodinated Contrast Shortage During the COVID-19 Pandemic: Single-Institution Experience.Journal of the American College of Radiology : JACR · 2022Article
- Article
- Article
- Changes in dispensing of medicines proposed for re-purposing in the first year of the COVID-19 pandemic in Australia.PloS one · 2022Article
- A review of key strategies to address the shortage of analgesics and sedatives in pediatric intensive care.Frontiers in pediatrics · 2022Review
- Changes in Purchases for Intensive Care Medicines During the COVID-19 Pandemic: A Global Time Series Study.Chest · 2021Article
- Medication Use Among Patients With COVID-19 in a Large, National Dataset: Cerner Real-World Data™.Clinical therapeutics · 2021Article
- Managing drug shortages during a pandemic: tocilizumab and COVID-19.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021Article
- The Impact of COVID-19 on Essential Medicines and Personal Protective Equipment Availability and Prices in Saudi Arabia.Healthcare (Basel, Switzerland) · 2021Article
- The Capacity of the Indonesian Healthcare System to Respond to COVID-19.Frontiers in public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critical drug shortages have been widely documented during the coronavirus disease 2019 (COVID-19) pandemic, particularly for IV sedatives used to facilitate mechanical ventilation. Surges in volume of patients requiring mechanical ventilation coupled with prolonged ventilator days and the high sedative dosing requirements observed quickly led to the depletion of "just-in-time" inventories typically maintained by institutions. This manuscript describes drug shortages in the context of global, manufacturing, regional and institutional perspectives in times of a worldwide crisis such as a pandemic. We describe etiologic factors that lead to drug shortages including issues related to supply (eg, manufacturing difficulties, supply chain breakdowns) and variables that influence demand (eg, volatile prescribing practices, anecdotal or low-level data, hoarding). In addition, we describe methods to mitigate drug shortages as well as conservation strategies for sedatives, analgesics and neuromuscular blockers that could readily be applied at the bedside. The COVID-19 pandemic has accentuated the need for a coordinated, multi-pronged approach to optimize medication availability as individual or unilateral efforts are unlikely to be successful.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.