ArticleCritical care medicine2020
Myoclonus in Patients With Coronavirus Disease 2019: A Multicenter Case Series.
Article in Critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Persistent Hiccups as an Atypical Presentation of SARS-CoV-2 Infection: A Systematic Review of Case Reports.Frontiers in neurology · 2022Pooled it
- Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review.Journal of medical case reports · 2021Pooled it
- Myoclonus and cerebellar ataxia associated with COVID-19: a case report and systematic review.Journal of neurology · 2021Pooled it
- Characterisation of internal tremors and vibration symptoms.BMJ open · 2023Article
- Movement Disorders and SARS-CoV-2.Movement disorders clinical practice · 2023Article
- COVID19-associated new-onset movement disorders: a follow-up study.Journal of neurology · 2023Article
- Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19.Internal medicine (Tokyo, Japan) · 2022Article
- Putative Role of the Lung-Brain Axis in the Pathogenesis of COVID-19-Associated Respiratory Failure: A Systematic Review.Biomedicines · 2022Review
- [COVID 19 and myoclonus, do hemodialysis patients have more risk?]Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia · 2021Article
- Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19).Journal of neurology · 2021Review
- Serum and CSF alpha-synuclein levels do not change in COVID-19 patients with neurological symptoms.Journal of neurology · 2021Article
- COVID-19-associated myoclonus in a series of five critically ill patients.Wiener klinische Wochenschrift · 2021Article
- Isolated generalized myoclonus immune-mediated by SARS-CoV-2: an illustrative videotaped case.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Generalised myoclonus associated with COVID-19 infection.BMJ case reports · 2021Article
- De Novo Movement Disorders and COVID-19: Exploring the Interface.Movement disorders clinical practice · 2021Review
- Neurologic Emergencies during the Coronavirus Disease 2019 Pandemic.Neurologic clinics · 2021Review
- Abnormal movements in hospitalized COVID-19 patients: A case series.Journal of the neurological sciences · 2021Article
- Neurologic Findings Among Inpatients With COVID-19 at a Safety-net US Hospital.Neurology. Clinical practice · 2021Article
- Myoclonus and Cerebellar Ataxia Associated with SARS-CoV-2 Infection: Case Report and Review of the Literature.European journal of case reports in internal medicine · 2021Article
- Movement Disorders Associated with COVID-19.Parkinson's disease · 2021Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesTo describe the risk factors for and outcomes after myoclonus in a cohort of patients with coronavirus disease 2019.
designMulticenter case series.
settingThree tertiary care hospitals in Massachusetts, Georgia, and Virginia. PATIENTS: Eight patients with clinical myoclonus in the setting of coronavirus disease 2019. INTERVENTIONS & MEASUREMENTS AND MAIN
resultsOutcomes in patients with myoclonus were variable, with one patient who died during the study period and five who were successfully extubated cognitively intact and without focal neurologic deficits. In five cases, the myoclonus completely resolved within 2 days of onset, while in three cases, it persisted for 10 days or longer. Seven patients experienced significant metabolic derangements, hypoxemia, or exposure to sedating medications that may have contributed to the development of myoclonus. One patient presented with encephalopathy and developed prolonged myoclonus in the absence of clear systemic provoking factors.
conclusionsOur findings suggest that myoclonus may be observed in severe acute respiratory syndrome coronavirus 2 infected patients, even in the absence of hypoxia. This association warrants further evaluation in larger cohorts to determine whether the presence of myoclonus may aid in the assessment of disease severity, neurologic involvement, or prognostication.
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