Evidence map›Paper›PMID 32804417›Full record

ReviewThe Journal of dermatology2020

Skin microbiota in health and disease: From sequencing to biology.

Thomas H A Ederveen, Jos P H Smits, Jos Boekhorst, Joost Schalkwijk, Ellen H van den Bogaard, Patrick L J M Zeeuwen

Abstract readReview
In one paragraph

Review in The Journal of dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  17. A Journey on the Skin Microbiome: Pitfalls and Opportunities.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas H A EderveenCenter for Molecular and Biomolecular Informatics (CMBI), Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center (Radboudumc), Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-0068-1275
Jos P H SmitsDepartment of Dermatology, RIMLS, Radboudumc, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-0915-8624
Jos BoekhorstCenter for Molecular and Biomolecular Informatics (CMBI), Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center (Radboudumc), Nijmegen, The Netherlands.
Joost SchalkwijkDepartment of Dermatology, RIMLS, Radboudumc, Nijmegen, The Netherlands.
Ellen H van den BogaardDepartment of Dermatology, RIMLS, Radboudumc, Nijmegen, The Netherlands.
Patrick L J M ZeeuwenDepartment of Dermatology, RIMLS, Radboudumc, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-6878-2438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbiota live in a closely regulated interaction with their environment, and vice versa. The presence and absence of microbial entities is greatly influenced by features of the niche in which they thrive. Characteristic of this phenomenon is that different human skin sites harbor niche-specific communities of microbes. Microbial diversity is considerable, and the current challenge lies in determining which microbes and (corresponding) functionality are of importance to a given ecological niche. Furthermore, as there is increasing evidence of microbial involvement in health and disease, the need arises to fundamentally understand microbiome processes for application in health care, nutrition and personal care products (e.g. diet, cosmetics, probiotics). This review provides a current overview of state-of-the-art sequencing-based techniques and corresponding data analysis methodology for profiling of complex microbial communities. Furthermore, we also summarize the existing knowledge regarding cutaneous microbiota and their human host for a wide range of skin diseases.

Indexed as

MicrobiotaProbioticsBiologyDietHumansSkinbioinformaticscutaneous diseasesmicrobiomicsnext-generation sequencingskin microbiota

Identifiers

PMID32804417
PMCPMC7589227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.