ArticleSports medicine - open2020
Assessment of exercise-induced stress by automated measurement of salivary cortisol concentrations within the circadian rhythm in Japanese female long-distance runners.
Article in Sports medicine - open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Pooled it
- Within-athlete association between morning on-track peak heart rate and same-day pre-performance salivary cortisol change under dry-track conditions: a multi-season single-case field study in a professional formula racing driver.Frontiers in physiology · 2026Article
- Sample Preparation for Metabolomic Analysis in Exercise Physiology.Biomolecules · 2024Review
- Can consumption of finger millet diet improve mental health status in athletes: a possible link with modulation of cortisol levels.Physical activity and nutrition · 2024Article
- Is Greener Better? Quantifying the Impact of a Nature Walk on Stress Reduction Using HRV and Saliva Cortisol Biomarkers.International journal of environmental research and public health · 2024Article
- Assessment of exercise-induced stress via automated measurement of salivary cortisol concentrations and the testosterone-to-cortisol ratio: a preliminary study.Scientific reports · 2023Article
- Assessment of Changes in Physiological Markers in Different Body Fluids at Rest and after Exercise.Nutrients · 2022Review
- Indigenous Land-Based Approaches to Well-Being: TheInternational journal of environmental research and public health · 2022Article
- Differences in stress response between two altitudes assessed by salivary cortisol levels within circadian rhythms in long-distance runners.Scientific reports · 2022Article
- The Effects of Physical Exercise on Saliva Composition: A Comprehensive Review.Dentistry journal · 2022Review
- Influence of Swimming Training Session on Selected Saliva Components in Youth Swimmers.Frontiers in physiology · 2022Article
- Player Chronotype Does Not Affect In-Game Performance during the Evening (>18:00 h) in Professional Male Basketball Players.Clocks & sleep · 2021Article
- The Impact of Sport Training on Oral Health in Athletes.Dentistry journal · 2021Review
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOvertraining syndrome, caused by prolonged excessive stress, results in reduced performance and cortisol responsiveness in athletes. It is necessary to collect saliva samples sequentially within circadian rhythm for assessing exercise stress by measuring cortisol concentrations, and automated cortisol measurements using electrochemiluminescence immunoassay (ECLIA) may be useful for measuring a large number of saliva samples. In this study, we evaluated the appropriate use of cortisol-based exercise stress assessment within the circadian rhythm, which may diagnose and prevent overtraining syndrome in athletes.
methodsWe collected saliva and sera from 54 healthy participants and analyzed the correlation between salivary cortisol concentrations measured by ECLIA and enzyme-linked immunosorbent assay (ELISA) or serum cortisol analysis. We also collected saliva continuously from 12 female long-distance runners on 2 consecutive days involving different intensities and types of exercise early in the morning and in the afternoon and measured salivary cortisol concentrations using ECLIA. Each exercise intensity of runners was measured by running velocities, Borg Scale score, and rate of change in the pulse rate by exercise.
resultsECLIA-based salivary cortisol concentrations correlated positively with those detected by ELISA (ρ = 0.924, p < 0.001) and serum cortisol (ρ = 0.591, p = 0.001). In long-distance runners, circadian rhythm of salivary cortisol, including the peak after waking and the decrease promptly thereafter, were detected on both days by continuous saliva sampling. The rates of change in salivary cortisol concentrations were significantly lower after an early morning exercise than after an afternoon exercise on both days (day 1, p = 0.002, and day 2, p = 0.003). In the early morning exercise, the rate of change in salivary cortisol concentration was significantly higher on day 1 than on day 2 (p = 0.034), similar to a significant difference in running velocities (p = 0.001).
conclusionsOur results suggest that automated ECLIA-based salivary cortisol measurements are able to detect the athletes' circadian rhythm and compare the exercise stress intensities at the same times on different days, even in the early morning, possibly leading to the prevention of overtraining syndrome.
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