Evidence map›Paper›PMID 32804291›Full record

ArticleAnnals of biomedical engineering2021

Patient-Specific Bicuspid Aortic Valve Biomechanics: A Magnetic Resonance Imaging Integrated Fluid-Structure Interaction Approach.

Monica Emendi, Francesco Sturla, Ram P Ghosh, Matteo Bianchi, Filippo Piatti, Francesca R Pluchinotta, Daniel Giese, Massimo Lombardi, Alberto Redaelli, Danny Bluestein

Open access · bronzeAbstract read
In one paragraph

Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
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  7. Review
  8. Simulation-based design of bicuspidization of the aortic valve.The Journal of thoracic and cardiovascular surgery · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Unusual Aneurysm of a Cervical Aortic Arch: Surgical Repair Improves Fluid Dynamics.World journal for pediatric & congenital heart surgery · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Monica Emendi *Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.
Francesco Sturla *3D and Computer Simulation Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Ram P GhoshDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA.
Matteo BianchiDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA.
Filippo Piatti3D and Computer Simulation Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Francesca R PluchinottaDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.
Daniel GieseSiemens Healthcare GmbH, Erlangen, Germany.
Massimo LombardiMultimodality Cardiac Imaging, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
Alberto RedaelliDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.
Danny BluesteinDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA. danny.bluestein@stonybrtook.edu.ORCID http://orcid.org/0000-0002-4014-2308
IRCCS Policlinico San Donato · ITStony Brook University · USPolitecnico di Milano · ITSiemens Healthineers (Germany) · DE

Funding

Biomechanical Approaches and Technologies for Enhancing TAVR OutcomesU01EB026414 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLUESTEIN, DANNY · 2018 to 2022
$3.8M
NIBIB NIH HHS BRPU01EB026414NIBIB NIH HHS U01 EB026414
6 · The paper itself

Abstract

Congenital bicuspid aortic valve (BAV) consists of two fused cusps and represents a major risk factor for calcific valvular stenosis. Herein, a fully coupled fluid-structure interaction (FSI) BAV model was developed from patient-specific magnetic resonance imaging (MRI) and compared against in vivo 4-dimensional flow MRI (4D Flow). FSI simulation compared well with 4D Flow, confirming direction and magnitude of the flow jet impinging onto the aortic wall as well as location and extension of secondary flows and vortices developing at systole: the systolic flow jet originating from an elliptical 1.6 cm

Indexed as

AdultAortic ValveBicuspid Aortic Valve DiseaseBiomechanical PhenomenaFemaleHemodynamicsHumansMagnetic Resonance ImagingPatient-Specific ModelingStress, Mechanical4D flowBicuspid aortic valveFluid–structure interactionMagnetic resonance imagingPatient-specific model

Identifiers

PMID32804291
PMCPMC7990108
OpenAlexW3064878964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.