Evidence map›Paper›PMID 32804011›Full record

ArticleGut microbes2020

Reuterin disrupts

Melinda A Engevik, Heather A Danhof, Ritu Shrestha, Alexandra L Chang-Graham, Joseph M Hyser, Anthony M Haag, Mahmoud A Mohammad, Robert A Britton, James Versalovic, Joseph A Sorg and 1 more

Abstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Bacterial vesicles-initiatedTheranostics · 2026
    Article
  14. Unravelling three-way interactions betweenJournal of medical microbiology · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. The Impact ofMicroorganisms · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Melinda A EngevikDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.ORCID 0000-0002-9742-9932
Heather A DanhofDepartment of Molecular Virology and Microbiology, Baylor College of Medicine , Houston, TX, USA.ORCID 0000-0002-6347-0021
Ritu ShresthaDepartment of Biology, Texas A&M University , College Station, TX, USA.
Alexandra L Chang-GrahamDepartment of Molecular Virology and Microbiology, Baylor College of Medicine , Houston, TX, USA.ORCID 0000-0002-3403-6787
Joseph M HyserDepartment of Molecular Virology and Microbiology, Baylor College of Medicine , Houston, TX, USA.
Anthony M HaagDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.
Mahmoud A MohammadDepartment of Pediatrics, Children's Nutrition Research Center, Baylor College of Medicine , Houston, TX, USA.
Robert A BrittonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine , Houston, TX, USA.ORCID 0000-0001-8983-9539
James VersalovicDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.ORCID 0000-0002-5765-4385
Joseph A SorgDepartment of Biology, Texas A&M University , College Station, TX, USA.ORCID 0000-0001-7822-2656
Jennifer K SpinlerDepartment of Pathology & Immunology, Baylor College of Medicine , Houston, TX, USA.ORCID 0000-0002-7830-7665

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
Project 3: Functional Microbiome and Host Signatures in Transition from Commensal to pathogenP01AI152999 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SAVIDGE, TOR C. · 2020 to 2025
$12.0M
Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8M
Research Training in Pediatrics GastroenterolgyT32DK007664 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI DOUGLAS G BURRIN · 1991 to 2026
$8.4M
Decoding Antibiotic-induced Susceptibility to Clostridium difficile InfectionU01AI124290 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A, GAREY, KEVIN W · 2016 to 2020
$7.9M
Training Supplement in Enteric Virus Exploitation of Calcium SignalingR01DK115507 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Joseph M. Hyser · 2018 to 2026
$5.0M
Mechanisms of Clostridium difficile spore germinationR01AI116895 · NIAID · TEXAS A&M UNIVERSITY · PI SORG, JOE · 2015 to 2024
$3.9M
Diet driven evolution of epidemic ribotypes of Clostridium difficileR01AI123278 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A · 2018 to 2022
$2.0M
Identifying the role of serotonin receptor 4 and trefoil factor 3 in intestinal wound repairK01DK123195 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ENGEVIK, MELINDA ANNE · 2020 to 2024
$612k
Metabolic adaptation drives pathogenicity of C. difficile epidemic strain RT078F32AI136404 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI DANHOF, HEATHER A. · 2019 to 2021
$191k
NIAID NIH HHS F32 AI136404NIAID NIH HHS P01 AI152999NIAID NIH HHS R01 AI116895NIAID NIH HHS R01 AI123278NIAID NIH HHS U01 AI124290NIDDK NIH HHS K01 DK123195NIDDK NIH HHS P30 DK056338NIDDK NIH HHS P30 DK123704NIDDK NIH HHS R01 DK115507NIDDK NIH HHS T32 DK007664
6 · The paper itself

Abstract

Antibiotic resistance is one of the world's greatest public health challenges and adjunct probiotic therapies are strategies that could lessen this burden.

Indexed as

Anti-Bacterial AgentsClostridioides difficileDrug SynergismEpithelial CellsGlyceraldehydeHumansLimosilactobacillus reuteriOrganoidsOxidative StressProbioticsPropaneReactive Oxygen SpeciesSpores, Bacterial3-hydroxypropionaldehydeAnti-Bacterial AgentsGlyceraldehydePropaneReactive Oxygen SpeciesClostridioides difficileenteroidsLactobacillus reuterimetabolismorganoidsoxidative stressprobioticsreactive oxygen speciesReuterin

Identifiers

PMID32804011
PMCPMC7524292

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.