Evidence map›Paper›PMID 32803755›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2021

Commentary: Substance use and the brain: it is not straightforward to differentiate cause from consequence - a commentary on Kim-Spoon et al. (2020).

Sylia Wilson

Open access · bronzeAbstract readComment
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Four dimensions of individualization in brain stimulation for psychiatric disorders: context, target, dose, and timing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Adolescent alcohol use is linked to disruptions in age-appropriate cortical thinning: an unsupervised machine learning approach.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sylia WilsonInstitute of Child Development, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0003-0144-524X
University of Minnesota · US

Funding

Brain Deviation Preceding Substance Use: An Offspring of Co-Twin Control StudyK01DA037280 · NIDA · UNIVERSITY OF MINNESOTA · PI WILSON, SYLIA · 2015 to 2019
$764k
Co-Twin Control Analysis of Effects of Alcohol on Brain Morphometry: Disentangling Cause From ConsequenceR21AA026632 · NIAAA · UNIVERSITY OF MINNESOTA · PI WILSON, SYLIA · 2018 to 2019
$477k
NIAAA NIH HHS R21 AA026632NIDA NIH HHS K01 DA037280
6 · The paper itself

Abstract

That substance abuse is associated with differences in brain structure and function, and related neurocognitive impairment is undisputed. Causally informative study designs, such as the prospective, longitudinal study leveraged by Kim-Spoon et al. (2020), as well as twin and family studies, are necessary for answering vexing but critical questions about substance use and the developing brain. Investigations that seek to differentiate cause from consequence and identify the factors that initiate the cycle of addiction have the potential to transform our understanding of the development of substance use and abuse, prompt revisions to current models of addiction, guide the most strategic preventive-intervention efforts, and ultimately improve the lives of millions of affected individuals and their families.

Indexed as

Substance-Related DisordersBrainHumansLongitudinal StudiesProspective StudiesTwins

Identifiers

PMID32803755
PMCPMC7887115
OpenAlexW3049092430

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.