Evidence map›Paper›PMID 32803699›Full record

ArticleInternational journal of hematology2020

Allogeneic hematopoietic stem cell transplantation in a prior lung transplant recipient.

Yuki Fujiwara, Ken-Ichi Matsuoka, Miki Iwamoto, Yuichi Sumii, Masaya Abe, Kentaro Mizuhara, Tomohiro Urata, Kyosuke Saeki, Yusuke Meguri, Noboru Asada and 8 more

Abstract readCase Reports
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In one paragraph

Article in International journal of hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Yuki FujiwaraDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Ken-Ichi MatsuokaDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan. k-matsu@md.okayama-u.ac.jp.
Miki IwamotoDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Yuichi SumiiDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Masaya AbeDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Kentaro MizuharaDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Tomohiro UrataDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Kyosuke SaekiDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Yusuke MeguriDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Noboru AsadaDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Daisuke EnnishiDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Hisakazu NishimoriDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Keiko FujiiDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Nobuharu FujiiDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Junichi SugitaDepartment of Hematology, Hokkaido University Hospital, Hokkaido, Japan.
Hajime KobayashiDepartment of Hematology, Obihiro Kosei Hospital, Hokkaido, Japan.
Takahiro OtoDepartment of Organ Transplant Center, Okayama University Hospital, Okayama, Japan.
Yoshinobu MaedaDepartment of Hematology and Oncology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
Okayama University Hospital · JPHokkaido University Hospital · JPObihiro Kosei General Hospital · JP

Funding

KAKENHI 20K08753
6 · The paper itself

Abstract

Hematological diseases after solid organ transplant (SOT) are an emerging issue as the number of long-term SOT survivors increases. Expertise in managing patients requiring allogeneic hematopoietic stem cell transplantation (HSCT) after SOT from independent donors is needed; however, clinical reports of HSCT after SOT are limited, and the feasibility and risk are not well understood. In particular, HSCT in prior lung transplant recipients is thought to be complicated as the lung is immunologically distinct and is constantly exposed to the surrounding environment. Herein, we describe a case of successful HSCT in a patient with myelodysplastic syndromes who had previously received a lung transplant from a deceased donor for bronchiolitis obliterans syndrome. Reports about cases of HSCT after lung transplant are quite rare; thus, we discuss the mechanisms of immune tolerance through the clinical course of our case. This case suggests that HSCT after SOT can be considered a therapeutic option in cases where the transplanted organ is functionally retained and the hematological disease is in remission.

Indexed as

Hematopoietic Stem Cell TransplantationLung TransplantationAdultBronchiolitis ObliteransFeasibility StudiesHumansImmune ToleranceLungMaleMyelodysplastic SyndromesTransplantation, HomologousTreatment OutcomeYoung AdultAllogeneic hematopoietic stem cell transplantationLung transplantMyelodysplastic syndromesTransplant tolerance

Identifiers

PMID32803699
OpenAlexW3049485478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.