Evidence map›Paper›PMID 32803443›Full record

ArticleClinical oral investigations2021

A case-control study of oral diseases and quality of life in individuals with rheumatoid arthritis and systemic lupus erythematosus.

Brena Rodrigues Manzano, Paulo Sérgio da Silva Santos, Matheus Henrique Bariquelo, Nathália Rodrigues Germano Merlini, Heitor Marques Honório, Cássia Maria Fischer Rubira

Abstract read
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In one paragraph

Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Oral Manifestations of Systemic Lupus Erythematosus: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Review
  3. Article
  4. Health-related quality of life in Chinese SLE patients: evidence from 1568 SLE patients and 2610 healthy controls.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brena Rodrigues ManzanoDepartment of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, Alameda Dr Octávio Pinheiro Brisolla, 9-75, Bauru, 17012-901, Brazil. brenamanzano@usp.br.ORCID http://orcid.org/0000-0003-0412-2243
Paulo Sérgio da Silva SantosDepartment of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, Alameda Dr Octávio Pinheiro Brisolla, 9-75, Bauru, 17012-901, Brazil.
Matheus Henrique BariqueloHospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC/USP), Silvio Marchione, 3-20, Bauru, 17012-900, Brazil.
Nathália Rodrigues Germano MerliniDepartment of Rheumatology, Bauru State Hospital, Eng. Luiz Edmundo Carrijo Coube, 1-100, Bauru, 17033-360, Brazil.
Heitor Marques HonórioDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr Octávio Pinheiro Brisolla, 9-75, Bauru, 17012-901, Brazil.
Cássia Maria Fischer RubiraDepartment of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, Alameda Dr Octávio Pinheiro Brisolla, 9-75, Bauru, 17012-901, Brazil.
Universidade de São Paulo · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (BR) 001
6 · The paper itself

Abstract

objectiveTo evaluate the impact of oral alterations on the quality of life (QoL) of individuals with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).

methodsA case-control study in 32 individuals with RA, 28 with SLE, and 29 in the control group (CG). The questionnaire SF-36 (Medical Outcomes Study Short-Form 36) was used to evaluate the health-related quality of life (HRQoL), and OHIP-14 (Oral Health Impact Profile-14) was used to evaluate the oral health-related quality of life (OHRQoL). The severity of xerostomia was evaluated by the Xerostomia Inventory (XI). In the clinical examination, decayed (D-T), missing(M-T), and filled teeth (F-T) (DMF-T), periodontal status, plaque index (PI), gingival index (GI), unstimulated whole salivary flow rate (UWSFR), and stimulated whole salivary flow rate (SWSFR) were also assessed. Data were analyzed by Student's t tests, chi-square test, Kruskal-Wallis test, ANOVA, Pearson's correlation, and Spearman's correlation.

resultsIndividuals with RA had a higher caries index (D-T/p = 0.004) and more frequent periodontal disease (PI/p = 0.017). In the SLE group, there was a significant lower salivary flow (SFR/p = 0.016, SFMS/p = 0.004) and severe xerostomia (p = 0.002). The impact of ORHQoL in individuals with RA occurred due to oral candidiasis, halitosis, and xerostomia, compromising the HRQoL. Overall, OHRQoL and HRQoL were more compromised in individuals with SLE, with xerostomia being the main oral problem.

conclusionIndividuals with RA and SLE present oral diseases with negative impact on their QoL. CLINICAL RELEVANCE: This study shows the main oral manifestations in rheumatic autoimmune diseases, with mainly xerostomia compromising the quality of life.

Indexed as

Arthritis, RheumatoidLupus Erythematosus, SystemicMouth DiseasesCase-Control StudiesHumansQuality of LifeSurveys and QuestionnairesOral healthOral health-related quality of lifeQuality of lifeRheumatoid arthritisSystemic lupus erythematosusXerostomia

Identifiers

PMID32803443
OpenAlexW3049755834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.