Evidence map›Paper›PMID 32803420›Full record

ReviewJournal of assisted reproduction and genetics2020

Maternal C-reactive protein and in vitro fertilization (IVF) cycles.

Fatemeh Diba-Bagtash, Azizeh Farshbaf-Khalili, Alyeh Ghasemzadeh, Laura Lotz, Amir Fattahi, Mahnaz Shahnazi, Ralf Dittrich

Open access · greenAbstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Fatemeh Diba-BagtashDepartment of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Azizeh Farshbaf-KhaliliPhysical Medicine and Rehabilitation Research Centre, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Alyeh GhasemzadehWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Laura LotzDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Amir FattahiWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. amirfattahi@gmail.com.ORCID http://orcid.org/0000-0002-5712-5336
Mahnaz ShahnaziDepartment of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran. mshahnazi@tbzmed.ac.ir.
Ralf DittrichDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Tabriz University of Medical Sciences · IRFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryo implantation is accompanied by a potent inflammatory response, and a gradient of cytokines and chemokines produced by endometrial cells supports the embryo-endometrial interaction. C-reactive protein (CRP) serves as an early marker of inflammation and recent studies have illustrated that controlled ovarian hyperstimulation (COH) could increase its levels. Interestingly, a high chance of pregnancy has been reported in women who had an elevated CRP level on the day of embryo transfer. It seems an elevated systemic inflammation in the in vitro fertilization (IVF) cycle can increase the implantation and pregnancy rates. However, the results regarding the association of CRP with ART outcomes are controversial. Therefore, in this review, we aimed to describe how CRP levels change during a cycle of IVF treatment and which factors can potentially affect this pattern of change. Furthermore, the association of CRP with ART outcomes has been discussed.

Indexed as

Fertilization in VitroAdultC-Reactive ProteinEmbryo ImplantationEmbryo TransferEndometriumFemaleHumansInflammationOvarian Hyperstimulation SyndromePregnancyC-Reactive ProteinARTBiomarkerCRPEmbryo implantationReproductive

Identifiers

PMID32803420
PMCPMC7642050
OpenAlexW3049369310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.