Evidence map›Paper›PMID 32803399›Full record

ReviewCellular and molecular life sciences : CMLS2021

Epidermal resident γδ T cell development and function in skin.

Yingping Xu, Peter Dimitrion, Steven Cvetkovski, Li Zhou, Qing-Sheng Mi

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. γδ T cells: origin and fate, subsets, diseases and immunotherapy.Signal transduction and targeted therapy · 2023
    Review
  8. From the Skin to Distant Sites: T Cells in Psoriatic Disease.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. γδ T Cells in Skin Inflammation.Critical reviews in immunology · 2022
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Yingping XuExperimental Research Center, Dermatology Hospital of Southern Medical University, and Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Peter DimitrionCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Steven CvetkovskiCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Li ZhouCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, MI, USA. lzhou1@hfhs.org.
Qing-Sheng MiCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, MI, USA. qmi1@hfhs.org.ORCID http://orcid.org/0000-0002-1411-6827
Henry Ford Health System · US

Funding

Henry Ford Health System T71016Henry Ford Health System T71017National Natural Science Foundation of China 81302603
6 · The paper itself

Abstract

Epidermal resident γδ T cells, or dendritic epidermal T cells (DETCs) in mice, are a unique and conserved population of γδ T cells enriched in the epidermis, where they serve as the regulators of immune responses and sense skin injury. Despite the great advances in the understanding of the development, homeostasis, and function of DETCs in the past decades, the origin and the underlying molecular mechanisms remain elusive. Here, we reviewed the recent research progress on DETCs, including their origin and homeostasis in the skin, especially at transcriptional and epigenetic levels, and discuss the involvement of DETCs in skin diseases.

Indexed as

AnimalsCell DifferentiationDisease Models, AnimalEpidermisEpigenesis, GeneticHumansIntraepithelial LymphocytesMiceSkinSkin DiseasesThymus GlandYolk SacDendritic epidermal T cells (DETCs)DevelopmentFunctionSkin diseasesγδ T cells

Identifiers

PMID32803399
PMCPMC11073445
OpenAlexW3049349117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.