ArticleArchives of gynecology and obstetrics2021
Identification of the optimal growth chart and threshold for the prediction of antepartum stillbirth.
Article in Archives of gynecology and obstetrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- New biomarkers for the detection of fetal death derived from large-scale proteomic analysis of maternal plasma.American journal of obstetrics and gynecology · 2026Article
- Do Birthweight-For-Gestational Age Centiles Predict Serious Neonatal Morbidity and Neonatal Mortality?Paediatric and perinatal epidemiology · 2026Article
- Differences in prediction of adverse perinatal outcome in term pregnancies by choice of fetal growth reference: A validation study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Association Between Sleep Quality and Duration During Pregnancy and Risk of Infant Being Small for Gestational Age: Prospective Birth Cohort Study.Healthcare (Basel, Switzerland) · 2024Article
- Reference Values for Birth Weight in Relation to Gestational Age in Poland and Comparison with the Global Percentile Standards.Journal of clinical medicine · 2023Article
- Reference values of fetal ultrasound biometry: results of a prospective cohort study in Lithuania.Archives of gynecology and obstetrics · 2022Article
- Predictive performance of newborn small for gestational age by a United States intrauterine vs birthweight-derived standard for short-term neonatal morbidity and mortality.American journal of obstetrics & gynecology MFM · 2022Observational
- FIGO (international Federation of Gynecology and obstetrics) initiative on fetal growth: best practice advice for screening, diagnosis, and management of fetal growth restriction.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the effect of the choice growth chart and threshold used to define small for gestational age (SGA) on the predictive value of SGA for placenta-related or unexplained antepartum stillbirth.
methodsA retrospective cohort study of all women with a singleton pregnancy who gave birth > 24 week gestation in a single center (2000-2016). The exposure of interest was SGA, defined as birth weight < 10th or < 25th centile according to three fetal growth charts (Hadlock et al., Radiology 181:129-133, 1991; intergrowth-21st (IG21), WHO 2017, and a Canadian birthweight-based reference-Kramer et al., Pediatrics 108:E35, 2001). The outcome of interest was antepartum stillbirth due to placental dysfunction or unknown etiology. Cases of stillbirth attributed to other specific etiologies were excluded.
resultsA total of 49,458 women were included in the cohort. There were 103 (0.21%) cases of stillbirth due to placental dysfunction or unknown etiology. For cases in the early stillbirth cluster (≤ 30 weeks), the detection rate was high and was similar for the three ultrasound-based fetal growth charts of Hadlock, IG21, and WHO (range 83.3-87.0%). In contrast, the detection rate of SGA for cases in the late stillbirth cluster (> 30 weeks) was low, being highest for WHO and Hadlock (36.7% and 34.7%, respectively), and lowest for IG21 (18.4%). Using a threshold of the 25th centile increased the detection rate for stillbirth by approximately 15-20% compared with that achieved by the 10th centile cutoff.
conclusionAt > 30 week gestation, the Hadlock or WHO fetal growth charts provided the best balance between detection rate and false positive rate for stillbirth.
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