ArticleAnalytical and bioanalytical chemistry2020
Direct sample introduction GC-MS/MS for quantification of organic chemicals in mammalian tissues and blood extracted with polymers without clean-up.
Article in Analytical and bioanalytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Characterizing the marine mammal exposome by iceberg modeling, linking chemical analysis andEnvironmental science. Processes & impacts · 2023Article
- Chemometers: an integrative tool for chemical assessment in multimedia environments.Chemical communications (Cambridge, England) · 2023Review
- Matrix compatibility of typical sol-gel solid-phase microextraction coatings in undiluted plasma and whole blood for the analysis of phthalic acid esters.Analytical and bioanalytical chemistry · 2022Article
- Calcium Nanoparticles Impregnated With Benzenedicarboxylic Acid: A New Approach to Alleviate Combined Stress of DDT and Cadmium inFrontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Solvent extracts of mammalian tissues and blood contain a large amount of co-extracted matrix components, in particular lipids, which can adversely affect instrumental analysis. Clean-up typically degrades non-persistent chemicals. Alternatively, passive sampling with the polymer polydimethylsiloxane (PDMS) has been used for a comprehensive extraction from tissue without altering the mixture composition. Despite a smaller fraction of matrix being co-extracted by PDMS than by solvent extraction, direct analysis of PDMS extracts was only possible with direct sample introduction (DSI) GC-MS/MS, which prevented co-extracted matrix components entering the system. Limits of quantitation (LOQ) ranged from 4 to 20 pg μL
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