Evidence map›Paper›PMID 32803292›Full record

Observational studyEuropean journal of clinical pharmacology2021

The 10-year trend in drug prescriptions for attention-deficit/hyperactivity disorder (ADHD) in Germany.

Thomas Grimmsmann, Wolfgang Himmel

Abstract readObservational Study
In one paragraph

Observational study in European journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  6. Patterns of prescription stimulant initiation before and during the COVID-19 pandemic: a population-based time-series analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas GrimmsmannGerman Health Insurance Medical Service (MDK) Mecklenburg-Vorpommern, 19059, Schwerin, Germany. t.grimmsmann@mdk-mv.de.ORCID https://orcid.org/0000-0002-0886-6162
Wolfgang HimmelDepartment of General Practice, University of Göttingen, Humboldtallee 38, 37073, Goettingen, Germany.ORCID https://orcid.org/0000-0003-3523-5486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to analyse whether the global trend in drug prescriptions for attention-deficit hyperactivity disorders (ADHD), as observed during the last years and often criticized as medicalization, have remained stable or shifted.

methodsThis observational study was based on a secondary analysis of data from a large German database including patients with an ADHD diagnosis between 2008 and 2018. Prescription data comprised all important ADHD drugs.

resultsA total of 620 practices delivered data from a total of 77,504 patients (31% of them females) with a diagnosis of AHDH. Nearly 38% (29,396/77,504) of all patients received, at least, one prescription for an ADHS medicine between 2008 and 2018. The number of patients receiving a drug steadily increased annually until 2012 and then slowly fell, but unevenly distributed across the age groups. While the number of younger patients ( ≤ 16 years) receiving a prescription fell by 24% and the defined daily doses (DDDs) remained stable, the number of patients between 17 and 24 years receiving a prescription increased by 113% and the DDDs by 150%. Respectively, the number of older adults (≥ 25 years) with a prescription increased by 355% and the DDDs by 515%. Nearly one-third of older adults received an ADHD medicine only once.

conclusionThe ever-increasing prescription of ADHD medicines stopped some years ago for children. ADHS and its pharmacological management are increasingly observed among older adolescents and adults, with a different pattern of drug persistence compared with children.

Indexed as

AdolescentAdultAtomoxetine HydrochlorideAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildChild, PreschoolDextroamphetamineDrug PrescriptionsFemaleGermanyGuanfacineHumansMaleMethylphenidatePractice Patterns, Physicians'Atomoxetine HydrochlorideCentral Nervous System StimulantsDextroamphetamineGuanfacineMethylphenidateAmbulatory careAttention-deficit disorder with hyperactivityCohort studiesDrug prescriptionsMethylphenidate

Identifiers

PMID32803292
PMCPMC7782395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.