Evidence map›Paper›PMID 32803165›Full record

ArticleRadiology. Imaging cancer2020

Assessment of Hepatocellular Carcinoma Response to

Stefanie J Hectors, Sara Lewis, Paul Kennedy, Octavia Bane, Daniela Said, Maxwell Segall, Myron Schwartz, Edward Kim, Bachir Taouli

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Imaging cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01871545 (Evaluation of HCC Response to Systemic Therapy With Quantitative MRI), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01871545 nacompletednot on this map

Evaluation of HCC Response to Systemic Therapy With Quantitative MRI

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2013 to 2018Enrolled84ConditionsHepatocellular Carcinoma, HCCArmsMagnetic Resonance Imaging
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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  6. DCE-MRI quantitative analysis and MRI-based radiomics for predicting the early efficacy of microwave ablation in lung cancers.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Stefanie J HectorsBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).ORCID 0000-0001-9457-6606
Sara LewisBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).ORCID 0000-0002-4713-6453
Paul KennedyBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).
Octavia BaneBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).
Daniela SaidBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).
Maxwell SegallBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).ORCID 0000-0001-5099-4857
Myron SchwartzBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).
Edward KimBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).
Bachir TaouliBiomedical Engineering and Imaging Institute (S.J.H., S.L., P.K., O.B., D.S., M. Segall, B.T.), Department of Diagnostic, Molecular and Interventional Radiology (S.J.H., S.L., P.K., O.B., D.S., M. Segall, E.K., B.T.), and Department of Liver Surgery, Recanati/Miller Transplantation Institute (M. Schwartz), Icahn School of Medicine at Mount Sinai, 1460 Madison Ave, New York, NY 10029; and Department of Radiology, Weill Cornell Medicine, New York, NY (S.J.H.).ORCID 0000-0001-6409-1333
Cornell University · US

Funding

Advanced Software for MRI, PET, SPECT and CT Image AnalysisU24EB028980 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RUSINEK, HENRY · 2019 to 2021
$1.2M
NIBIB NIH HHS U24 EB028980
6 · The paper itself

Abstract

Purpose: To quantify diffusion and perfusion changes in hepatocellular carcinoma (HCC) induced by yttrium 90 ( Materials and Methods: Institutional review board approval was obtained for this prospective study (clinical trial registry NCT01871545). Twenty-four participants with HCC (mean age, 69 years ± 9 [standard deviation], 18 men) underwent multiparametric MRI, including IVIM DWI and gadoxetic acid DCE MRI before ( Results: Twenty-five HCCs were analyzed (mean size, 3.6 cm ± 1.9). Radioembolization resulted in significantly decreased perfusion (DCE MRI arterial flow, Conclusion: Diffusion and perfusion MRI can be used to evaluate the response of HCC to radioembolization. Pretreatment DCE MRI histogram parameters may be useful for radioembolization treatment stratification.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAgedContrast MediaHumansMagnetic Resonance ImagingMaleProspective StudiesYttrium RadioisotopesContrast MediaYttrium Radioisotopes

Identifiers

PMID32803165
PMCPMC7398117
OpenAlexW3044255374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.