Evidence map›Paper›PMID 32803132›Full record

ReviewHemaSphere2020

How We Manage Patients With Chronic Lymphocytic Leukemia During the SARS-CoV-2 Pandemic.

Davide Rossi, Mazyar Shadman, Adalgisa Condoluci, Jennifer R Brown, John C Byrd, Gianluca Gaidano, Michael Hallek, Peter Hillmen, Anthony Mato, Emili Montserrat and 1 more

Abstract readReview
In one paragraph

Review in HemaSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. [Single-center study of COVID-19 in patients with chronic lymphocytic leukemia].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Managing toxicities of Bruton tyrosine kinase inhibitors.Hematology. American Society of Hematology. Education Program · 2020
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Davide RossiDivision of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Mazyar ShadmanDivision of Medical Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Adalgisa CondoluciDivision of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Jennifer R BrownChronic Lymphocytic Leukemia Center, Division of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.
John C ByrdThe Ohio State University Comprehensive Cancer Center and Division of Hematology, Columbus, Ohio, USA.
Gianluca GaidanoDivision of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
Michael HallekCenter of Integrated Oncology Cologne Bonn and German CLL Study Group, University of Cologne, Cologne, Germany.
Peter HillmenHaematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom.
Anthony MatoMemorial Sloan Kettering Cancer Center, New York, New York, USA.
Emili MontserratHospital Clinic, Barcelona, Spain.
Paolo GhiaDivision of Experimental Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.

Funding

Targeted Therapy for LeukemiaR35CA197734 · NCI · UNIVERSITY OF CINCINNATI · PI BYRD, JOHN C. · 2015 to 2021
$6.6M
NCI NIH HHS R35 CA197734
6 · The paper itself

Abstract

Infections are a major cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL). These can be exacerbated by anti-leukemic treatments. In addition, the typical patients with CLL already have fragilities and background risk factors that apply to the general population for severe COVID-19. On these bases, patients with CLL may experience COVID-19 morbidity and mortality. Recurrent seasonal epidemics of SARS-CoV-2 are expected, and doctors taking care of patients with CLL must be prepared for the possibility of substantial resurgences of infection and adapt their approach to CLL management accordingly. In this Guideline Article, we aim at providing clinicians with a literature-informed expert opinion on the management of patients with CLL during SARS-CoV-2 epidemic.

Identifiers

PMID32803132
PMCPMC7410019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.