Evidence map›Paper›PMID 32803125›Full record

ReviewSN applied sciences2020

The recent advances in the mathematical modelling of human pluripotent stem cells.

L E Wadkin, S Orozco-Fuentes, I Neganova, M Lako, A Shukurov, N G Parker

Abstract readReview
In one paragraph

Review in SN applied sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L E WadkinSchool of Mathematics Statistics and Physics, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0001-7355-2023
S Orozco-FuentesSchool of Mathematics Statistics and Physics, Newcastle University, Newcastle upon Tyne, UK.
I NeganovaInstitute of Cytology, RAS, St. Petersburg, Russia.
M LakoInstitute of Genetic Medicine, Newcastle Univeristy, Newcastle upon Tyne, UK.
A ShukurovSchool of Mathematics Statistics and Physics, Newcastle University, Newcastle upon Tyne, UK.
N G ParkerSchool of Mathematics Statistics and Physics, Newcastle University, Newcastle upon Tyne, UK.

Funding

Medical Research Council G0301182
6 · The paper itself

Abstract

Human pluripotent stem cells hold great promise for developments in regenerative medicine and drug design. The mathematical modelling of stem cells and their properties is necessary to understand and quantify key behaviours and develop non-invasive prognostic modelling tools to assist in the optimisation of laboratory experiments. Here, the recent advances in the mathematical modelling of hPSCs are discussed, including cell kinematics, cell proliferation and colony formation, and pluripotency and differentiation.

Indexed as

Human pluripotent stem cellsMathematical modelling

Identifiers

PMID32803125
PMCPMC7391994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.