Evidence map›Paper›PMID 32803118›Full record

ArticleInternational journal of reproductive biomedicine2020

Semen analysis of subfertility caused by testicular carcinoma.

Behrooz Ghasemi, Alimohammad Mosadegh Mehrjardi, Carolyn Jones, Nasrin Ghasemi

Open access · goldAbstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Behrooz GhasemiMaternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, Reproductive Medicine, School of Medical Sciences, St Mary's Hospital, University of Manchester, Manchester, UK.
Alimohammad Mosadegh MehrjardiMaternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, Reproductive Medicine, School of Medical Sciences, St Mary's Hospital, University of Manchester, Manchester, UK.
Carolyn JonesDivision of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Central Manchester University Hospital NHS Foundation Trust, Manchester Academic Health Sciences Centre, St Mary's Hospital Manchester, UK.
Nasrin GhasemiAbortion Research Centre, Reproductive Sciences Institute, Shahid Sadoughi University of Medical Science, Yazd, Iran.
Tehran University of Medical Sciences · IRUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility is a common problem in testicular cancer. Affected men often decide to undergo sperm banking before chemo/radiotherapy. The cumulative effects of therapy can considerably reduce fertility.

objectiveTesticular cancers impair fertilizing ability, even before diagnosis. This study tries to verify individual traits and semen quality in patients with testicular cancer. MATERIALS AND

methodsThis observational study analyzed 190 semen of patients with testicular cancer (16 to 47 yr old) referred to the sub-fertility laboratory at the St. Mary hospital for semen banking prior to treatment carcinoma. Several aspects of their semen analyses were examined. The cases were divided into four different categories: seminoma, teratoma, mixed germ cell tumors and others.

resultsThe results showed that 23 cases were azoospermic, and 13 of the patients who were not azoospermic, their sperm of "normal" morphology were too few to count. Among patients that could produce spermatozoa, 59.4% had a sperm concentration of

conclusionAbnormal spermatogenesis is seen in most patients with testicular cancer before treatment with radiation, chemotherapy, or surgery. The causes of poor semen quality in cancer patients are not well-understood, but the patients with impaired spermatogenesis should have precise examination to find out the correct diagnosis of problem and preserve the fertility before any treatment.

Indexed as

InfertilitySemen analysesSpermatogenesis.Testicular cancer

Identifiers

PMID32803118
PMCPMC7385918
OpenAlexW3044759018

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.