Evidence map›Paper›PMID 32803097›Full record

ArticleJournal of the Endocrine Society2020

Adrenal Corticomedullary Mixed Tumor Associated With the

Maki Kanzawa, Hidenori Fukuoka, Akane Yamamoto, Kentaro Suda, Katsumi Shigemura, Shigeo Hara, Naoko Imagawa, Ryuko Tsukamoto, Yayoi Aoyama, Yasuhiro Nakamura and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Mixed corticomedullary tumor of the adrenal gland.Frontiers in endocrinology · 2022
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Maki KanzawaDepartment of Diagnostic Pathology, Kobe University Hospital, Kobe, Japan.ORCID 0000-0003-2806-2011
Hidenori FukuokaDivision of Diabetes and Endocrinology, Kobe University Hospital, Kobe, Japan.ORCID 0000-0001-9255-653X
Akane YamamotoDivision of Diabetes and Endocrinology, Kobe University Hospital, Kobe, Japan.
Kentaro SudaDivision of Diabetes and Endocrinology, Kobe University Hospital, Kobe, Japan.ORCID 0000-0001-6734-5183
Katsumi ShigemuraDivision of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, Kobe, Japan.
Shigeo HaraDivision of Urology, Department of Surgery Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Naoko ImagawaDepartment of Diagnostic Pathology, Kobe University Hospital, Kobe, Japan.
Ryuko TsukamotoDepartment of Diagnostic Pathology, Kobe University Hospital, Kobe, Japan.
Yayoi AoyamaDepartment of Diagnostic Pathology, Kobe City Medical Center General Hospital, Kobe, Japan.
Yasuhiro NakamuraDepartment of Pathology, Tohoku University Hospital, Sendai, Japan.
Masato FujisawaDivision of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, Kobe, Japan.
Wataru OgawaDivision of Pathology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Yutaka TakahashiDivision of Pathology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.ORCID 0000-0002-1337-9246
Tomoo ItohDepartment of Diagnostic Pathology, Kobe University Hospital, Kobe, Japan.
Kobe University Hospital · JPKobe University · JPTohoku Medical and Pharmaceutical University · JPKobe City Medical Center General Hospital · JPTohoku University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenal corticomedullary mixed tumors (CMMTs) are extremely rare; with only 20 cases being reported to date, the pathogenesis has remained elusive. A 31-year-old woman developed gestational hypertension with psychiatric disturbances persistent to postpartum and was diagnosed with pheochromocytoma, for which adrenalectomy was performed. Histological findings showed mixed adrenocortical adenoma and pheochromocytoma. Double immunostaining of inhibin and INSM1 (insulinoma-associated protein 1) showed that the 2 tumor components had distinct functional properties. Exome analysis of peripheral leukocytes and tumor (singular, as anatomically it is only 1 mass) revealed a homozygous germline

Indexed as

adrenal glandcorticomedullary mixed tumorFGFR4-G388R variant

Identifiers

PMID32803097
PMCPMC7417000
OpenAlexW3045352220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.