Evidence map›Paper›PMID 32803089›Full record

ArticleJournal of the Endocrine Society2020

ApoB48-Lipoproteins Are Associated with Cardiometabolic Risk in Adolescents with and without Polycystic Ovary Syndrome.

Donna F Vine, Lawrence J Beilin, Sally Burrows, Rae-Chi Huang, Martha Hickey, Roger Hart, Spencer D Proctor, Trevor A Mori

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Biomarkers in Polycystic Ovary Syndrome.Current opinion in physiology · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Donna F VineMetabolic and Cardiovascular Disease Laboratory, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0001-7816-3422
Lawrence J BeilinMedical School, University of Western Australia, Royal Perth Hospital Unit, Perth, Australia.
Sally BurrowsMedical School, University of Western Australia, Royal Perth Hospital Unit, Perth, Australia.
Rae-Chi HuangThe Telethon Kids Institute, University of Western Australia, Perth, Australia.
Martha HickeyDepartment of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Victoria, Australia.ORCID 0000-0002-3941-082X
Roger HartMedical School, University of Western Australia, Royal Perth Hospital Unit, Perth, Australia.
Spencer D ProctorMetabolic and Cardiovascular Disease Laboratory, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.
Trevor A MoriMedical School, University of Western Australia, Royal Perth Hospital Unit, Perth, Australia.
The University of Western Australia · AUUniversity of Alberta · CARoyal Women's Hospital · AUThe Kids Research Institute Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAdolescents with polycystic ovary syndrome (PCOS) have increased incidence of cardiometabolic risk factors including dyslipidemia. Atherogenic apolipoprotein (apo) B-lipoprotein remnants are associated with increased cardiovascular disease (CVD) risk.

objectiveThe aim of this study was to determine the concentrations of fasting plasma apoB-lipoprotein remnants, apoB48 and apoB100, and their association with cardiometabolic risk factors and androgen indices in adolescent girls with and without PCOS. DESIGN SETTING AND

participantsParticipants (n = 184) aged 17 years were recruited in the Menstruation in Teenagers Study from the Western Australian Pregnancy Cohort (Raine) Study. THE

main outcome measuresFasting plasma apo-B48 and -B100 lipoprotein remnant concentrations in adolescent girls with and without PCOS.

resultsFasting plasma apoB48-lipoprotein remnants but not apoB100-lipoprotein remnants were elevated in adolescent girls with increased cardiometabolic risk compared with those with lower cardiometabolic risk (13.91 ± 5.06 vs 12.09 ± 4.47 µg/mL,

Indexed as

adiposityadolescenceApoB-lipoprotein remnantsatherosclerosiscardiometabolic risk factorsmetabolic syndromepolycystic ovary syndrome

Identifiers

PMID32803089
PMCPMC7417872
OpenAlexW3032147690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.