Evidence map›Paper›PMID 32803041›Full record

ArticleACS omega2020

A Copper(II) Macrocycle Complex for Sensing Biologically Relevant Organic Anions in a Competitive Fluorescence Assay: Oxalate Sensor or Urate Sensor?

David Hontz, Jayden Hensley, Kayla Hiryak, Jennifer Lee, Jared Luchetta, Maria Torsiello, Michael Venditto, Del Lucent, William Terzaghi, Donald Mencer and 2 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

David HontzDepartment of Chemistry & Biochemistry, College of Science and Engineering, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Jayden HensleyDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Kayla HiryakDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Jennifer LeeDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Jared LuchettaDepartment of Chemistry & Biochemistry, College of Science and Engineering, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Maria TorsielloDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Michael VendittoDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Del LucentDepartment of Electrical Engineering and Physics, College of Science and Engineering, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
William TerzaghiDepartment of Biology, College of Science and Engineering, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Donald MencerDepartment of Chemistry & Biochemistry, College of Science and Engineering, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Ajay BommareddyDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Adam L VanWertDepartment of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes University, 84 W South St., Wilkes-Barre, Pennsylvania 18766, United States.
Wilkes University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence sensing of oxalate has garnered some attention in the past two decades as a result of this anion's prominence and impact on society. Previous work on oxalate sensors and other divalent anion sensors has led to the conclusion that the sensors are selective for the anion under investigation. However, sensor selectivity is often determined by testing against a relatively small array of "guest" molecules or analytes and studies often exclude potentially interfering compounds. For example, studies on oxalate sensors have excluded compounds such as citrate and urate, which are anions in the biological matrices where oxalate is measured (

Identifiers

PMID32803041
PMCPMC7424571
OpenAlexW3046184419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.