Evidence map›Paper›PMID 32802999›Full record

ArticleJournal of preventive medicine and hygiene2020

Invasive meningococcal disease in Italy: from analysis of national data to an evidence-based vaccination strategy.

S Igidbashian, L Bertizzolo, A Tognetto, C Azzari, P Bonanni, P Castiglia, M Conversano, S Esposito, G Gabutti, G Icardi and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of preventive medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Preventing invasive meningococcal disease in early infancy.Human vaccines & immunotherapeutics · 2022
    Review
  3. Article
  4. Knowledge and Behaviours towards Immunisation Programmes: Vaccine Hesitancy during the COVID-19 Pandemic Era.International journal of environmental research and public health · 2022
    Article
  5. Meningococcal Disease in Pediatric Age: A Focus on Epidemiology and Prevention.International journal of environmental research and public health · 2022
    Article
  6. Review
  7. Article
  8. [Journal of preventive medicine and hygiene · 2021
    Article
  9. Meningococcal Carriage in 'Men Having Sex With Men' With Pharyngeal Gonorrhoea.Frontiers in cellular and infection microbiology · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

S IgidbashianSanofi Pasteur, Milan, Italy.
L BertizzoloSanofi Pasteur, Milan, Italy.
A TognettoSection of Hygiene, Institute of Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
C AzzariDepartment of Health Sciences, University of Florence, Italy.
P BonanniDepartment of Health Sciences, University of Florence, Italy.
P CastigliaDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, Italy.
M ConversanoDepartment of Prevention, Local Health Authority of Taranto, Italy.
S EspositoPediatric Clinic, Pietro Barilla Children's Hospital, University of Parma, Italy.
G GabuttiDepartment of Medical Sciences, University of Ferrara, Italy.
G IcardiDepartment of Health Sciences, University of Genoa, Italy; IRCCS San Martino Policlinic Hospital, Genoa, Italy.
P L LopalcoDepartment of Translational Research, New Technologies in Medicine & Surgery, University of Pisa, Italy.
F VitaleDepartment of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Italy.
S ParisiSanofi Pasteur, Milan, Italy.
G Checcucci LisiSanofi Pasteur, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInvasive meningococcal disease (IMD) is one of the most severe vaccine-preventable disease not yet under control. In Italy, although different anti-meningococcal vaccines are available, their offer among regions is heterogeneous. The aim of this study is to describe the epidemiology of IMD in Italy based on analysis of national surveillance data for 2011-2017 to optimize the vaccination strategy.

methodsIMD surveillance data from the Italian National Health Institute were analysed. Microsoft Excel was used to present trend analysis, stratifying by age and serogroups.

resultsIn Italy, during the period 2011-2017, the incidence of IMD increased from 0.25 cases/100,000 inhabitants in 2011 to 0.33 cases/100,000 in 2017. Most cases after 2012 were caused by non-B serogroups. The number of cases in subjects aged 25-64 years increased steadily after 2012 (36 cases in 2011, 79 in 2017), mostly due to non-B serogroups, representing more than 65% of cases in those aged 25+ years.

conclusionsIn the period from 2011 to 2017, the incidence of IMDs increased in Italy. The increase, probably due also to a better surveillance, highlights the importance of the disease in the adult population and the high level of circulation of non-B serogroups in particular after 2012. Our analysis supports an anti-meningococcal vaccination plan in Italy that should include the highest number of preventable serogroups and be aimed at vaccinating a wider population through a multicohort strategy.

Indexed as

Evidence-Based MedicineAdolescentAdultChildChild, PreschoolDatabases, FactualHumansIncidenceInfantItalyMeningococcal InfectionsMeningococcal VaccinesMiddle AgedPopulation SurveillanceYoung AdultMeningococcal VaccinesAnti-meningococcal vaccination strategiesEpidemiologyInvasive meningococcal diseasesSurveillance system

Identifiers

PMID32802999
PMCPMC7419122

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.