Evidence map›Paper›PMID 32802958›Full record

ArticleNPJ precision oncology2020

Small cell transformation of

Jessica J Lin, Adam Langenbucher, Pranav Gupta, Satoshi Yoda, Isobel J Fetter, Marguerite Rooney, Andrew Do, Marina Kem, Kylie Prutisto Chang, Audris Y Oh and 11 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in NPJ precision oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  5. JTO clinical and research reports · 2026
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  9. Frontiers in oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Jessica J LinDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Adam LangenbucherDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Pranav GuptaDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Satoshi YodaDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.ORCID 0000-0003-4201-1392
Isobel J FetterDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Marguerite RooneyDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.ORCID 0000-0002-4996-0737
Andrew DoDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.ORCID 0000-0002-5782-5818
Marina KemHarvard Medical School, Boston, MA USA.
Kylie Prutisto ChangDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.ORCID 0000-0003-2845-2458
Audris Y OhDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Emily ChinDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Dejan JuricDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Ryan B CorcoranDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.ORCID 0000-0001-8173-5778
Ibiayi Dagogo-JackDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Justin F GainorDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
James R StoneHarvard Medical School, Boston, MA USA.
Jochen K LennerzHarvard Medical School, Boston, MA USA.ORCID 0000-0003-2434-4978
Michael S LawrenceDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Aaron N HataDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Mari Mino-KenudsonHarvard Medical School, Boston, MA USA.
Alice T ShawDepartment of Medicine, Massachusetts General Hospital, Boston, MA USA.
Harvard University · US

Funding

Dana Farber/Harvard Cancer Consortium Career Development Program in Clinical OncologyK12CA087723 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI David Tsai Ting · 2002 to 2026
$17.9M
Overcoming Resistance Mechanisms to Anaplastic Lymphoma Kinase InhibitorsR01CA164273 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Aaron N Hata, Jessica Jiyeong Lin · 2012 to 2026
$5.5M
Illuminating the evolutionary history of colorectal cancer metastasis: basic principles and clinical applicationsR37CA225655 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI NAXEROVA, KAMILA · 2018 to 2024
$3.0M
NCI NIH HHS K12 CA087723NCI NIH HHS R01 CA164273NCI NIH HHS R37 CA225655
6 · The paper itself

Abstract

Histologic transformation from non-small cell to small cell lung cancer has been reported as a resistance mechanism to targeted therapy in

Indexed as

Lung cancer

Identifiers

PMID32802958
PMCPMC7400592
OpenAlexW3047494686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.