Evidence map›Paper›PMID 32802943›Full record

ArticleNPJ breast cancer2020

The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density.

Dane Cheasley, Lisa Devereux, Siobhan Hughes, Carolyn Nickson, Pietro Procopio, Grant Lee, Na Li, Vicki Pridmore, Kenneth Elder, G Bruce Mann and 9 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Cohort Profile: Lifepool.International journal of epidemiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Dane CheasleyCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-1170-4690
Lisa DevereuxCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0003-2435-5888
Siobhan HughesCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Carolyn NicksonCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC Australia.
Pietro ProcopioCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC Australia.
Grant LeeCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC Australia.
Na LiCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0003-1578-9561
Vicki PridmoreBreastScreen Victoria, Carlton South, VIC Australia.
Kenneth ElderDepartment of Surgery, University of Melbourne, Melbourne, VIC Australia.
G Bruce MannSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC Australia.
Tanjina KaderCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-1463-7593
Simone M RowleyCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Stephen B FoxDepartment of Pathology, Peter MacCallum Cancer Centre, and University of Melbourne, Melbourne, VIC Australia.
David ByrneDepartment of Pathology, Peter MacCallum Cancer Centre, and University of Melbourne, Melbourne, VIC Australia.ORCID 0000-0002-9258-3252
Hugo SaundersCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Kenji M FujiharaCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-8387-4912
Belle LimCancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.
Kylie L Gorringe *Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC Australia.
Ian G Campbell *Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC Australia.ORCID 0000-0002-7773-4155
Peter MacCallum Cancer Centre · AUThe University of Melbourne · AURoyal Women's Hospital · AUThe University of Sydney · AUBreastscreen Victoria · AU

Funding

EPA EP-C-15-004
6 · The paper itself

Abstract

Mammographic density (MD) influences breast cancer risk, but how this is mediated is unknown. Molecular differences between breast cancers arising in the context of the lowest and highest quintiles of mammographic density may identify the mechanism through which MD drives breast cancer development. Women diagnosed with invasive or in situ breast cancer where MD measurement was also available (

Indexed as

Breast cancerCancer genomics

Identifiers

PMID32802943
PMCPMC7414106
OpenAlexW3048145377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.