ReviewBioMed research international2020
Conservative Treatment of Interstitial Ectopic Pregnancy with the Combination of Mifepristone and Methotrexate: Our Experience and Review of the Literature.
Review in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The efficacy of mifepristone combined with methotrexate for the treatment of ectopic pregnancy: a systematic review and meta-analysis.Annals of medicine · 2022Pooled it
- Conservative treatment of cesarean scar pregnancy with the combination of methotrexate and mifepristone: A systematic review.Women's health (London, England)Pooled it
- The Role of Hysteroscopy for the Treatment of Interstitial Ectopic Pregnancy: A Systematic Review.Journal of clinical medicine · 2026Review
- Review
- A case report of intramural pregnancy with uterine rupture: a warning signal from ineffective evacuation.Frontiers in medicine · 2026Article
- Conservative medical treatment cured an interstitial tubal pregnancy complicated by a uterine artery pseudoaneurysm: a case report.Frontiers in medicine · 2026Article
- Risk factors for misdiagnosis of interstitial ectopic pregnancy.Emergency radiology · 2025Article
- Tubal Ectopic Pregnancy: From Diagnosis to Treatment.Biomedicines · 2025Review
- Successful Management of Cervical and Tubal Stump Double Pregnancy after Assisted Reproductive Technologies Using Multiple High Doses of Methotrexate: A Case Report.Iranian journal of medical sciences · 2024Article
- Article
- The Use of Methotrexate and Mifepristone for Treatment of Interstitial Pregnancies: An Overview of Effectiveness and Complications.Journal of clinical medicine · 2023Review
- Interstitial Ectopic Pregnancy-Case Reports and Medical Management.Medicina (Kaunas, Lithuania) · 2023Article
- Hysteroscopic removal of intrauterine device in early pregnancy.BMC women's health · 2022Article
- Interstitial ectopic pregnancy rupture at 17 weeks of gestation: A case report and literature review.Case reports in women's health · 2022Article
- Interstitial Pregnancy Treated with Mifepristone and Methotrexate with High Serum β-hCG Level in a Patient Wishing to Preserve Fertility: Time to Define Standardized Criteria for Medical/Surgical Therapy?International journal of environmental research and public health · 2022Article
- Surgical Treatment Following Failed Medical Treatment of an Interstitial Pregnancy.Medicina (Kaunas, Lithuania) · 2022Article
- Therapeutic effect of laparoscopic salpingotomy vs. salpingectomy on patients with ectopic pregnancy: A systematic review and meta-analysis.Frontiers in surgery · 2022Review
- Interstitial Ectopic Pregnancy: The Role of Mifepristone in the Medical Treatment.International journal of environmental research and public health · 2021Review
- Management of Non-Tubal Ectopic Pregnancies: A Single Center Experience.Diagnostics (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInterstitial pregnancy (IP) is an ectopic pregnancy (EP) located in the portion of the fallopian tube that penetrates the uterine muscular layer. Incidence increased in the last two decades with the widespread use of the assisted reproductive techniques. It is estimated in 1-6% of all the EPs, with a maternal mortality rate of 2.0-2.5%. Clinical presentation, gestational age at diagnosis, beta-human chorionic gonadotropin ( MATERIALS AND
methodsA literature search was carried out on MEDLINE, EMBASE, and PUBMED. We identified two cases of IP referred to the Institute for Maternal and Child Burlo Garofolo, Trieste. Data related to clinical presentation,
resultsIn the first case,
conclusionsClinical management of IP remains a debated topic. In selected cases, a systemic multidose MTX regimen combined with a single oral dose of Mifepristone could be considered also in the presence of high serum
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.