ArticleMaxillofacial plastic and reconstructive surgery2020
Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study.
Article in Maxillofacial plastic and reconstructive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Micronutrient intake and food insecurity among mothers of infants with orofacial clefts: a cross-sectional study in Iran.Scientific reports · 2026Article
- Antenatal care and childbirth experience among parents of children with orofacial clefts: an observational study.BMC oral health · 2026Observational
- The burden and care of orofacial cleft in Rwanda: a scoping review.BMC oral health · 2025Article
- Assessment of Parental Risk Factors Involved in Orofacial Clefts in Hail, Saudi Arabia: A Retrospective Cohort Study.Cureus · 2024Article
- Orofacial Clefts and Maternal Risk Factors: A Population-Based Case-Control Study.Children (Basel, Switzerland) · 2024Article
- Characteristics of Factors Influencing the Occurrence of Cleft Lip and/or Palate: A Case Analysis and Literature Review.Children (Basel, Switzerland) · 2024Article
- Epidemiological and clinical evaluation of patients with a cleft in lower saxony Germany: a mono-center analysis.Clinical oral investigations · 2023Article
- COVID-19 related risk factors and their association with non-syndromic orofacial clefts in five Arab countries: a case-control study.BMC oral health · 2023Article
- Maternal stress as a risk factor for non-syndromic orofacial clefts: Systematic review andThe Saudi dental journal · 2023Review
- Epidemiological and Spatiotemporal Descriptive Analysis of Patients with Nonsyndromic Cleft Lip and/or Palate: A 12-Year Retrospective Study in Southern Iran.BioMed research international · 2023Article
- Orofacial Clefting in Van der Woude's Syndrome.Eplasty · 2023Article
- Modifiable Risk Factors of Non-Syndromic Orofacial Clefts: A Systematic Review.Children (Basel, Switzerland) · 2022Review
- Parental Risk Factors and Child Birth Data in a Matched Year and Sex Group Cleft Population: A Case-Control Study.International journal of environmental research and public health · 2021Article
- Validation of Thymocyte Selection-associated High-mobility Group Box-3 Gene Mutation and Risk Identification in Non-syndromic Cleft Lip and Palate Deformities in Malay Patients - A Retrospective Study.Annals of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden.
objectivesThis study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. STUDY
designA total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child's sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy.
resultsAnalysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (
conclusionsMultiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn.
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