ArticleJournal of biomedical physics & engineering2020
New MRI Finding in Migraineurs: Mesial Temporal Sclerosis.
Article in Journal of biomedical physics & engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Astrocytes as critical players of the fine balance between inhibition and excitation in the brain: spreading depolarization as a mechanism to curb epileptic activity.Frontiers in network physiology · 2024Review
- Functional connectivity of the language area in migraine: a preliminary classification model.BMC neurology · 2023Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBased on our experience, a noticeable number of migraineurs without history of epilepsy disclose mesial temporal sclerosis (MTS) on their brain MRI.
objectiveThis prospective study was conducted to assess the frequency of MTS in migraineurs and also determine the ratio of unilateral and bilateral cases. MATERIAL AND
methodsIn this cross sectional study, the frequency of MTS in MRI of 84 migraine patients, who had symptoms for at least 2 years, assessed. Brain MRI was done with T1 and T2 weighted protocols. Two radiologists separately interpreted findings, defining MTS as presence of any of hippocampal atrophy, increased T2 signal of hippocampus, decreased T1 signal of hippocampus or loss of internal architecture. Patients who radiologists had not agreement on their diagnoses excluded. Stat analysis done using '
resultsEleven patients were excluded due to non-accordant interpretation of MRI findings by the two examining radiologists. MTS was detected in 14 out of 73 patients (19%). Bilateral involvement of mesial temporal lobe was seen in 6 (8%) patients (M 67%, F 33%). Five cases (7%) had unilateral left MTS (M 67%, F 33%) while 3 (4%) were affected with right-sided MTS (M 33%, F 67%). These findings highly suggest association of MTS and Migraine (P-value <0.0001).
conclusionWhile MTS is a prevalent finding in migraineurs, incidental finding of MTS in MRI should suspect physicians of migraine as well as temporal lobe epilepsy. MTS can be proposed as an etiology of migraine but most likely, consequence of it.
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